Biology:MYO9B

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

MYO9B is a gene that encodes the Myosin-IXb protein.

Further reading

• "Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.". Proc. Natl. Acad. Sci. U.S.A. 91 (14): 6549–53. 1994. doi:10.1073/pnas.91.14.6549. PMID 8022818. Bibcode: 1994PNAS...91.6549B. 
• "Human myosin-IXb, an unconventional myosin with a chimerin-like rho/rac GTPase-activating protein domain in its tail.". J. Cell Sci. 109 (3): 653–61. 1997. doi:10.1242/jcs.109.3.653. PMID 8907710. 
• "Human myosin-IXb is a mechanochemically active motor and a GAP for rho.". J. Cell Sci. 111 (7): 941–50. 1998. doi:10.1242/jcs.111.7.941. PMID 9490638. 
• "Cloning of the murine unconventional myosin gene Myo9b and identification of alternative splicing.". Gene 240 (2): 389–98. 2000. doi:10.1016/S0378-1119(99)00459-X. PMID 10580159. 
• "Myosin-IXb is a single-headed and processive motor.". J. Biol. Chem. 277 (14): 11679–83. 2002. doi:10.1074/jbc.M111173200. PMID 11801597. 
• "Myosin IXb is a single-headed minus-end-directed processive motor.". Nat. Cell Biol. 4 (4): 302–6. 2002. doi:10.1038/ncb774. PMID 11901422. 
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• "A major non-HLA locus in celiac disease maps to chromosome 19.". Gastroenterology 125 (4): 1032–41. 2003. doi:10.1016/S0016-5085(03)01205-8. PMID 14517787. 
• "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039. 
• "BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity.". J. Biol. Chem. 280 (11): 10128–34. 2005. doi:10.1074/jbc.M413415200. PMID 15644318. 
• "Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution.". Science 308 (5725): 1149–54. 2005. doi:10.1126/science.1108625. PMID 15790807. Bibcode: 2005Sci...308.1149C. 
• "Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect.". Nat. Genet. 37 (12): 1341–4. 2006. doi:10.1038/ng1680. PMID 16282976. 
• "A unique ATP hydrolysis mechanism of single-headed processive myosin, myosin IX.". J. Biol. Chem. 281 (8): 4949–57. 2006. doi:10.1074/jbc.M509141200. PMID 16338935. 
• "A unique mechanism for the processive movement of single-headed myosin-IX.". Biochem. Biophys. Res. Commun. 343 (4): 1159–64. 2006. doi:10.1016/j.bbrc.2006.03.057. PMID 16616011. 
• "Association analysis of MYO9B gene polymorphisms with celiac disease in a Swedish/Norwegian cohort.". Hum. Immunol. 67 (4–5): 341–5. 2006. doi:10.1016/j.humimm.2006.03.020. PMID 16720215. 
• "A family-based study does not confirm the association of MYO9B with celiac disease in the Italian population.". Genes Immun. 7 (7): 606–8. 2007. doi:10.1038/sj.gene.6364331. PMID 16943798. 
• "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
• "Genetic variation in myosin IXB is associated with ulcerative colitis.". Gastroenterology 131 (6): 1768–74. 2007. doi:10.1053/j.gastro.2006.09.011. PMID 17087940. 
• "No evidence of association of the MYO9B polymorphisms with celiac disease in the Spanish population.". Tissue Antigens 68 (6): 489–92. 2007. doi:10.1111/j.1399-0039.2006.00699.x. PMID 17176439. 

External links

• Overview of all the structural information available in the PDB for UniProt: Q13459 (Human Unconventional myosin-IXb (MYO9B)) at the PDBe-KB.