Biology:Mammaglobin-B
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Mammaglobin-B also known as secretoglobin family 2A member 1 is a protein that in humans is encoded by the SCGB2A1 gene.[1][2]
SCGB2A1 and breast cancer
SCGB2A1 expression is highly specific of mammary tissue, and has been used for identification and detection of disseminated breast cancer cells.[3]
References
- ↑ "Identification of mammaglobin B, a novel member of the uteroglobin gene family". Genomics 54 (1): 70–8. Jan 1999. doi:10.1006/geno.1998.5539. PMID 9806831.
- ↑ "Entrez Gene: SCGB2A1 secretoglobin, family 2A, member 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4246.
- ↑ Lacroix, M (2006). "Significance, detection and markers of disseminated breast cancer cells". Endocrine-Related Cancer (Bioscientifica) 13 (4): 1033–1067. doi:10.1677/ERC-06-0001. PMID 17158753.
Further reading
- "Establishment of the human reflex tear two-dimensional polyacrylamide gel electrophoresis reference map: new proteins of potential diagnostic value.". Electrophoresis 18 (15): 2811–5. 1998. doi:10.1002/elps.1150181516. PMID 9504814.
- "Lipophilin, a novel heterodimeric protein of human tears.". FEBS Lett. 432 (3): 163–7. 1998. doi:10.1016/S0014-5793(98)00852-7. PMID 9720917.
- "Lipophilins: human peptides homologous to rat prostatein.". Biochem. Biophys. Res. Commun. 256 (1): 147–55. 1999. doi:10.1006/bbrc.1999.0274. PMID 10066439.
- "Lacryglobin in human tears, a potential marker for cancer.". Clin. Experiment. Ophthalmol. 29 (3): 161–3. 2001. doi:10.1046/j.1442-9071.2001.00408.x. PMID 11446459.
- "Purification and characterization of the mammaglobin/lipophilin B complex, a promising diagnostic marker for breast cancer.". Biochemistry 41 (21): 6714–22. 2002. doi:10.1021/bi0159884. PMID 12022875.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages.". Nat. Med. 9 (2): 191–7. 2003. doi:10.1038/nm822. PMID 12539042.
- "Dysregulated secretoglobin expression in human lung cancers.". Lung Cancer 41 (1): 49–56. 2003. doi:10.1016/S0169-5002(03)00126-0. PMID 12826312.
- "RT-PCR for mammaglobin genes, MGB1 and MGB2, identifies breast cancer micrometastases in sentinel lymph nodes.". Am. J. Clin. Pathol. 121 (5): 637–43. 2004. doi:10.1309/MMAC-TXT5-5L8Q-TKC1. PMID 15151203.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Secretoglobin 2A1 is under selective androgen control mediated by a peculiar binding site for Sp family transcription factors.". Mol. Endocrinol. 19 (12): 2964–78. 2006. doi:10.1210/me.2004-0408. PMID 16020486.
- "Identification of mammaglobin as a novel serum marker for breast cancer.". Clin. Cancer Res. 11 (18): 6528–35. 2005. doi:10.1158/1078-0432.CCR-05-0415. PMID 16166429.
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