Biology:Mcr1
From HandWiki
MCR1 is a gene found in yeast. It is used to understand cell cycle checkpoints.[1] Researchers are working to find a way to use this gene to create anti-cancer drugs.[1]
Function
The most common function is found during the cell cycle when mutations occur because it becomes activated without phosphorylation and turns on Cds1.[2] It also works with Cdk1 to get rid of the mutations that occur. If MCR 1 is not present in the cell these check points do not work properly.[1]
References
- ↑ 1.0 1.1 1.2 "Activation of the DNA damage checkpoint in mutants defective in DNA replication initiation". Mol. Biol. Cell 19 (10): 4374–82. October 2008. doi:10.1091/mbc.E08-01-0020. PMID 18667534. PMC 2555949. http://www.molbiolcell.org/cgi/pmidlookup?view=long&pmid=18667534.
- ↑ "MCR1 Mcr1p [Saccharomyces cerevisiae"]. Entrez Gene. National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/gene/853707.
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