Biology:Mutant protein
From HandWiki
A mutant protein is the protein product encoded by a gene with mutation.[1] Mutated protein can have single amino acid change (minor, but still in many cases significant change leading to disease) or wide-range amino acid changes by e.g. truncation of C-terminus after introducing premature stop codon.
See also
- Site-directed mutagenesis
- Phi value analysis
- missense mutation
- nonsense mutation
- point mutation
- frameshift mutation
- silent mutation
- single-nucleotide polymorphism
References
- ↑ Wang, Qing; Chaerkady, Raghothama; Wu, Jian; Hwang, Hee Jung; Papadopoulos, Nick; Kopelovich, Levy; Maitra, Anirban; Matthaei, Hanno et al. (2011). "Mutant proteins as cancer-specific biomarkers". Proceedings of the National Academy of Sciences of the United States of America 108 (6): 2444–9. doi:10.1073/pnas.1019203108. PMID 21248225. Bibcode: 2011PNAS..108.2444W.
 |  |
