Biology:NEO1
 Generic protein structure example |
Neogenin is a protein that in humans is encoded by the NEO1 gene.[1][2]
Interactions
NEO1 has been shown to interact with PTK2.[3] Also Neogenin receptor is pointed as a component of the mechanisms that determine skeletal cell fusion via RGMa (repulsive guidance molecule a) binding. [4]
References
- ↑ "Identification and characterization of neogenin, a DCC-related gene". Oncogene 14 (10): 1129–36. Apr 1997. doi:10.1038/sj.onc.1200935. PMID 9121761.
- ↑ "Entrez Gene: NEO1 neogenin homolog 1 (chicken)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4756.
- ↑ "Focal adhesion kinase in netrin-1 signaling". Nat. Neurosci. 7 (11): 1204–12. Nov 2004. doi:10.1038/nn1330. PMID 15494733.
- ↑ Do Carmo Costa, Alinne; Copola, Aline Gonçalves Lio; Carvalho e Souza, Clara; Nogueira, Júlia Meireles; Silva, Gerluza Aparecida Borges; Jorge, Erika Cristina (2021). "RGMa can induce skeletal muscle cell hyperplasia via association with neogenin signalling pathway". In Vitro Cellular & Developmental Biology - Animal 57 (4): 415–427. doi:10.1007/s11626-021-00555-9. PMID 33748906. https://doi.org/10.1007/s11626-021-00555-9.
Further reading
- "Neogenin, an avian cell surface protein expressed during terminal neuronal differentiation, is closely related to the human tumor suppressor molecule deleted in colorectal cancer.". J. Cell Biol. 127 (6 Pt 2): 2009–20. 1995. doi:10.1083/jcb.127.6.2009. PMID 7806578.
- "Deleted in Colorectal Cancer (DCC) encodes a netrin receptor.". Cell 87 (2): 175–85. 1996. doi:10.1016/S0092-8674(00)81336-7. PMID 8861902.
- "Molecular characterization of human neogenin, a DCC-related protein, and the mapping of its gene (NEO1) to chromosomal position 15q22.3-q23.". Genomics 41 (3): 414–21. 1997. doi:10.1006/geno.1997.4688. PMID 9169140.
- "Netrin-3, a mouse homolog of human NTN2L, is highly expressed in sensory ganglia and shows differential binding to netrin receptors.". J. Neurosci. 19 (12): 4938–47. 1999. doi:10.1523/JNEUROSCI.19-12-04938.1999. PMID 10366627.
- "Netrin-1/neogenin interaction stabilizes multipotent progenitor cap cells during mammary gland morphogenesis.". Dev. Cell 4 (3): 371–82. 2003. doi:10.1016/S1534-5807(03)00054-6. PMID 12636918.
- "Profiling follicle stimulating hormone-induced gene expression changes in normal and malignant human ovarian surface epithelial cells.". Oncogene 22 (27): 4243–56. 2003. doi:10.1038/sj.onc.1206437. PMID 12833147.
- "RGM and its receptor neogenin regulate neuronal survival.". Nat. Cell Biol. 6 (8): 749–55. 2004. doi:10.1038/ncb1157. PMID 15258591.
- "Focal adhesion kinase in netrin-1 signaling.". Nat. Neurosci. 7 (11): 1204–12. 2005. doi:10.1038/nn1330. PMID 15494733.
- "Neogenin expression may be inversely correlated to the tumorigenicity of human breast cancer.". BMC Cancer 5: 154. 2006. doi:10.1186/1471-2407-5-154. PMID 16324219.
- "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.". J. Proteome Res. 4 (6): 2070–80. 2006. doi:10.1021/pr0502065. PMID 16335952.
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