Biology:NXF2
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Nuclear RNA export factor 2 is a protein that in humans is encoded by the NXF2 gene.[1][2][3]
Function
This gene is one of a family of nuclear RNA export factor genes. It encodes a protein that is involved in mRNA export, is located in the nucleoplasm, and is associated with the nuclear envelope. Alternative splicing seems to be a common mechanism in this gene family. Two variants have been found for this gene.[3]
Interactions
NXF2 has been shown to interact with NUP214.[1]
References
- ↑ 1.0 1.1 "TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture". Molecular and Cellular Biology 20 (23): 8996–9008. Dec 2000. doi:10.1128/MCB.20.23.8996-9008.2000. PMID 11073998.
- ↑ "An abundance of X-linked genes expressed in spermatogonia". Nature Genetics 27 (4): 422–426. Apr 2001. doi:10.1038/86927. PMID 11279525.
- ↑ 3.0 3.1 "Entrez Gene: NXF2 nuclear RNA export factor 2". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56001.
Further reading
- "Identification of an NTF2-related factor that binds Ran-GTP and regulates nuclear protein export". Molecular and Cellular Biology 19 (12): 8616–24. Dec 1999. doi:10.1128/MCB.19.12.8616. PMID 10567585.
- "NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation". Current Biology 11 (18): 1381–1391. Sep 2001. doi:10.1016/S0960-9822(01)00419-5. PMID 11566096.
- "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–1178. Oct 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
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