Biology:OR2H1
 Generic protein structure example |
Olfactory receptor 2H1 is a protein that in humans is encoded by the OR2H1 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
See also
References
Further reading
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Complex transcription and splicing of odorant receptor genes.". J. Biol. Chem. 278 (22): 19691–701. 2003. doi:10.1074/jbc.M212424200. PMID 12637542.
- "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. 2003. doi:10.1038/nature02055. PMID 14574404. Bibcode: 2003Natur.425..805M.
- "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. 2004. doi:10.1073/pnas.0307882100. PMID 14983052. Bibcode: 2004PNAS..101.2584M.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Genomic architecture of MHC-linked odorant receptor gene repertoires among 16 vertebrate species.". Immunogenetics 62 (9): 569–84. 2010. doi:10.1007/s00251-010-0468-6. PMID 20680261.
External links
- OR2H1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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