Biology:Ovorubin
| Ovorubin | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | |||||||
| Symbol | PcOvo | ||||||
| Alt. symbols | PcPV1 | ||||||
| PDB | J7HZ90; J7I5Z5 | ||||||
| UniProt | J7I2T6 | ||||||
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Ovorubin (PcOvo or PcPV1) is the most abundant perivitellin (>60 % total protein) of the perivitelline fluid from Pomacea canaliculata snail eggs. This glyco-lipo-caroteno protein complex is a approx. 300 kDa multimer of a combination of multiple copies of six different ~30 kDa subunits.[1]
Together with the other perivitellins from Pomacea canaliculata eggs, ovorubin serves a nutrient source for developing embryos, notably to the intermediate and late stages.[2] Moreover, after hatching, the protein is still detected in the lumen of the digestive gland ready to be endocytosed, therefore, acting as a nutrient source for the newly hatched snail.[2]
Ovorubin contains carbohydrates and carotenoid pigments as main prosthetic groups, [3] which are related to many physiological roles on Pomacea aerial egg-laying strategy. Given that carbohydrates tend to retain water, the high glycosylation of ovorubin (~17 % w/w) was proposed as an embryo defense against water loss.[3] The carotenoid pigments stabilized by ovorubin also provide the eggs of antioxidant and photoprotective capacities, crucial roles to cope with the harsh conditions of the aerial environment.[2][4][5][6][7][excessive citations] The presence of carotenoid pigments is also responsible for the brightly reddish coloration of Ovorubin, and therefore snail eggs, which was related to a warning coloration (aposematism) advertising predators about the presence of deterrents.[8][9] In fact, field evidence of egg unpalatability is provided by the fact that most animals foraging in habitats where the apple snails live ignore these eggs.[10]
Like most other studied perivitellins from Pomacea snails, ovorubin is highly stable in a wide range of pH values and withstands gastrointestinal digestion, characteristics associated with an antinutritive defense system that deters predation by lowering the nutritional value of the eggs.[11][12]
References
- ↑ "Lipoproteins of the egg perivitelline fluid of Pomacea canaliculata snails (Mollusca: Gastropoda)". The Journal of Experimental Zoology 276 (5): 307–14. December 1996. doi:10.1002/(SICI)1097-010X(19961201)276:5<307::AID-JEZ1>3.0.CO;2-S. PMID 8972583.
- ↑ 2.0 2.1 2.2 "Biochemical composition and energy sources during embryo development and in early juveniles of the snail Pomacea canaliculata (Mollusca: Gastropoda)" (in en). Journal of Experimental Zoology 280 (6): 375–383. 1998. doi:10.1002/(SICI)1097-010X(19980415)280:6<375::AID-JEZ1>3.0.CO;2-K. ISSN 1097-010X.
- ↑ 3.0 3.1 "Characterization of the major egg glycolipoproteins from the perivitellin fluid of the apple snail Pomacea canaliculata". Molecular Reproduction and Development 68 (3): 359–64. July 2004. doi:10.1002/mrd.20078. PMID 15112330.
- ↑ "Ovorubin, a chromoprotein from the eggs of the gastropod mollusc Pomacea canaliculata". Proceedings of the Royal Society of London. Series B, Biological Sciences 149 (937): 571–87. December 1958. doi:10.1098/rspb.1958.0093. PMID 13623805. Bibcode: 1958RSPSB.149..571C.
- ↑ "Metabolism of ovorubin, the major egg lipoprotein from the apple snail". Molecular and Cellular Biochemistry 243 (1–2): 9–14. January 2003. doi:10.1023/A:1021616610241. PMID 12619883.
- ↑ "Antioxidant defense system in the apple snail eggs, the role of ovorubin". Archives of Biochemistry and Biophysics 422 (1): 1–8. February 2004. doi:10.1016/j.abb.2003.11.018. PMID 14725852.
- ↑ "Astaxanthin binding and structural stability of the apple snail carotenoprotein ovorubin". Archives of Biochemistry and Biophysics 460 (1): 107–12. April 2007. doi:10.1016/j.abb.2006.12.033. PMID 17324373.
- ↑ "Egg carotenoproteins in neotropical Ampullariidae (Gastropoda: Arquitaenioglossa)". Comparative Biochemistry and Physiology. Toxicology & Pharmacology 146 (1–2): 158–67. 2007-07-01. doi:10.1016/j.cbpc.2006.10.013. PMID 17320485.
- ↑ "Insights from an Integrated View of the Biology of Apple Snails (Caenogastropoda: Ampullariidae)". Malacologia 58 (1–2): 245–302. 2015. doi:10.4002/040.058.0209. ISSN 0076-2997. https://www.arca.fiocruz.br/handle/icict/12732.
- ↑ "Defenses of the Florida Apple Snail Pomacea Paludosa" (in en). Behaviour 40 (3–4): 175–214. 1971-01-01. doi:10.1163/156853971X00384. ISSN 0005-7959.
- ↑ "Global shape and pH stability of ovorubin, an oligomeric protein from the eggs of Pomacea canaliculata". The FEBS Journal 275 (18): 4522–30. September 2008. doi:10.1111/j.1742-4658.2008.06595.x. PMID 18673387.
- ↑ "The role of the proteinase inhibitor ovorubin in apple snail eggs resembles plant embryo defense against predation". PLOS ONE 5 (12): e15059. December 2010. doi:10.1371/journal.pone.0015059. PMID 21151935. Bibcode: 2010PLoSO...515059D.
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