Biology:PIBF1

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Progesterone-induced-blocking factor 1 is a protein that in humans is encoded by the PIBF1 gene.[1][2] It has been shown to localize to the centrosome[3] and has also been named CEP90.[4]


References

  1. "A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes". Hum Genet 110 (2): 111–21. Apr 2002. doi:10.1007/s00439-001-0646-6. PMID 11935316. https://zenodo.org/record/1232709. 
  2. "Entrez Gene: C13orf24 chromosome 13 open reading frame 24". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10464. 
  3. "PIBF (progesterone induced blocking factor) is overexpressed in highly proliferating cells and associated with the centrosome.". Int. J. Cancer 112 (1): 51–60. 2004. doi:10.1002/ijc.20326. PMID 15305375. 
  4. Kim, K.; Rhee, K. (2011). "The pericentriolar satellite protein CEP90 is crucial for integrity of the mitotic spindle pole". Journal of Cell Science 124 (Pt 3): 338–347. doi:10.1242/jcs.078329. PMID 21224392. 

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Further reading