Biology:R1162-like plasmid antisense RNA
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| R1162-like plasmid antisense RNA | |
|---|---|
 Predicted secondary structure and sequence conservation of Plasmid_R1162 | |
| Identifiers | |
| Symbol | Plasmid_R1162 |
| Rfam | RF00043 |
| Other data | |
| RNA type | Gene; antisense |
| Domain(s) | Bacteria |
| SO | 0001263 |
| PDB structures | PDBe |
R1162-like plasmid antisense RNA is a 75-base RNA molecule which negatively regulates the RepI region of the plasmid.[1] The protein product of this gene region, along with another protein, controls the copy number of the 8.75kB R1162 plasmid.[2]
Experimental evidence has shown that in Escherichia coli, when levels of this RNA are decreased, the plasmid copy number of R1162 is increased.[1]
References
- ↑ 1.0 1.1 "Copy-number of broad host-range plasmid R1162 is regulated by a small RNA". Nucleic Acids Research 14 (20): 8027–8046. October 1986. doi:10.1093/nar/14.20.8027. PMID 2430262.
- ↑ "Copy number of the broad host-range plasmid R1162 is determined by the amounts of essential plasmid-encoded proteins". Journal of Molecular Biology 185 (4): 755–767. October 1985. doi:10.1016/0022-2836(85)90060-9. PMID 2932556.
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