Biology:REG4
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 Generic protein structure example |
Regenerating islet-derived protein 4 is a protein that in humans is encoded by the REG4 gene.[1][2][3]
References
- ↑ "Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family: Reg IV". Biochim Biophys Acta 1518 (3): 287–93. Apr 2001. doi:10.1016/s0167-4781(00)00284-0. PMID 11311942.
- ↑ "Reg IV, a new member of the regenerating gene family, is overexpressed in colorectal carcinomas". Int J Cancer 103 (2): 185–93. Nov 2002. doi:10.1002/ijc.10788. PMID 12455032.
- ↑ "Entrez Gene: REG4 regenerating islet-derived family, member 4". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=83998.
Further reading
- Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Kämäräinen M; Heiskala K; Knuutila S et al. (2003). "RELP, a Novel Human Reg-Like Protein with Up-Regulated Expression in Inflammatory and Metaplastic Gastrointestinal Mucosa". Am. J. Pathol. 163 (1): 11–20. doi:10.1016/S0002-9440(10)63625-5. PMID 12819006.
- Zhang Y; Lai M; Lv B et al. (2003). "Overexpression of Reg IV in colorectal adenoma". Cancer Lett. 200 (1): 69–76. doi:10.1016/S0304-3835(03)00460-9. PMID 14550954.
- Ota T; Suzuki Y; Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. 2005. doi:10.1110/ps.04682504. PMID 15340161.
- Gerhard DS; Wagner L; Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Gu Z; Rubin MA; Yang Y et al. (2005). "Reg IV: a promising marker of hormone refractory metastatic prostate cancer". Clin. Cancer Res. 11 (6): 2237–43. doi:10.1158/1078-0432.CCR-04-0356. PMID 15788672.
- Bishnupuri KS; Luo Q; Murmu N et al. (2006). "Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas". Gastroenterology 130 (1): 137–49. doi:10.1053/j.gastro.2005.10.001. PMID 16401477.
- Gregory SG; Barlow KF; McLay KE et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414. Bibcode: 2006Natur.441..315G.
- Takehara A; Eguchi H; Ohigashi H et al. (2006). "Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4". Cancer Sci. 97 (11): 1191–7. doi:10.1111/j.1349-7006.2006.00297.x. PMID 16918991.
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