Biology:Ring finger protein 167
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 Generic protein structure example |
Ring finger protein 167 is a protein that in humans is encoded by the RNF167 gene. [1]
Function
RNF167 is an E3 ubiquitin ligase that interacts with TSSC5 (SLC22A18; MIM 602631) and, together with UBCH6 (UBE2E1; MIM 602916), facilitates TSSC5 polyubiquitylation (Yamada and Gorbsky, 2006 [PubMed 16314844]).[supplied by OMIM, Mar 2008].
References
Further reading
- "Ubiquitin ligase RNF167 regulates AMPA receptor-mediated synaptic transmission". Proc. Natl. Acad. Sci. U.S.A. 109 (47): 19426–31. November 2012. doi:10.1073/pnas.1217477109. PMID 23129617. Bibcode: 2012PNAS..10919426L.
- "Goliath family E3 ligases regulate the recycling endosome pathway via VAMP3 ubiquitylation". EMBO J. 32 (4): 524–37. February 2013. doi:10.1038/emboj.2013.1. PMID 23353890.
- "Tumour-associated mutations of PA-TM-RING ubiquitin ligases RNF167/RNF13 identify the PA domain as a determinant for endosomal localization". Biochem. J. 459 (1): 27–36. April 2014. doi:10.1042/BJ20131067. PMID 24387786.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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