Biology:SEPT4

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Septin-4 is a protein that in humans is encoded by the SEPT4 gene.[1][2]

Function

This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. The protein encoded by this gene is thought to be part of a complex involved in cytokinesis. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.[2]

References

  1. "Characterization of a novel gene, PNUTL2, on human chromosome 17q22-q23 and its exclusion as the Meckel syndrome gene". Genomics 55 (1): 122–5. January 1999. doi:10.1006/geno.1998.5612. PMID 9889007. 
  2. 2.0 2.1 "Entrez Gene: SEPT4 septin 4". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5414. 

Further reading