Biology:SFI1
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Sfi1 homolog, spindle assembly associated (yeast) is a protein that in humans is encoded by the SFI1 gene. [1] It localizes to the centriole, and its S. pombe ortholog has been shown to be involved in spindle pole body duplication.[2] SFI1 forms a complex with centrin 2.[3]
References
- ↑ "Entrez Gene: Sfi1 homolog, spindle assembly associated (yeast)". https://www.ncbi.nlm.nih.gov/gene/9814. Retrieved 2014-06-25.
- ↑ "Molecular mechanisms that restrict yeast centrosome duplication to one event per cell cycle". Current Biology 24 (13): 1456–66. July 2014. doi:10.1016/j.cub.2014.05.032. PMID 24954044.
- ↑ "Structure, dynamics and thermodynamics of the human centrin 2/hSfi1 complex". Journal of Molecular Biology 395 (1): 191–204. January 2010. doi:10.1016/j.jmb.2009.10.041. PMID 19857500. https://zenodo.org/record/45696.
Further reading
- "Structure, dynamics and thermodynamics of the human centrin 2/hSfi1 complex". Journal of Molecular Biology 395 (1): 191–204. January 2010. doi:10.1016/j.jmb.2009.10.041. PMID 19857500. https://zenodo.org/record/45696.
- "The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion". The Journal of Cell Biology 151 (4): 837–46. November 2000. doi:10.1083/jcb.151.4.837. PMID 11076968.
- "The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation". EMBO Reports 7 (4): 418–24. April 2006. doi:10.1038/sj.embor.7400639. PMID 16462731.
- "Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation". Developmental Cell 5 (1): 113–25. July 2003. doi:10.1016/S1534-5807(03)00193-X. PMID 12852856.
- "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". The EMBO Journal 19 (23): 6569–81. December 2000. doi:10.1093/emboj/19.23.6569. PMID 11101529.
- "Sfi1p has conserved centrin-binding sites and an essential function in budding yeast spindle pole body duplication". The Journal of Cell Biology 162 (7): 1211–21. September 2003. doi:10.1083/jcb.200307064. PMID 14504268.
- "Docking motif-guided mapping of the interactome of protein phosphatase-1". Chemistry & Biology 16 (4): 365–71. April 2009. doi:10.1016/j.chembiol.2009.02.012. PMID 19389623.
- "Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex". Molecular Biology of the Cell 13 (9): 3235–45. September 2002. doi:10.1091/mbc.E02-02-0112. PMID 12221128.
- "Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function". The Journal of Cell Biology 129 (6): 1617–28. June 1995. doi:10.1083/jcb.129.6.1617. PMID 7790358.
Rüthnick D, Vitale J, Neuner A, Schiebel E. The N-terminus of Sfi1 and yeast centrin Cdc31 provide the assembly site for a new spindle pole body. J Cell Biol. 2021 Mar 1;220(3):e202004196. doi: 10.1083/jcb.202004196. PMID: 33523111; PMCID: PMC7852455.
External links
- Overview of all the structural information available in the PDB for UniProt: A8K8P3 (Protein SFI1 homolog) at the PDBe-KB.
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