Biology:Staphylococcus-1 RNA motif
| Staphylococcus-1 | |
|---|---|
 Consensus secondary structure and sequence conservation of Staphylococcus-1 RNA | |
| Identifiers | |
| Symbol | Staphylococcus-1 |
| Rfam | RF03112 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | 0001263 |
| PDB structures | PDBe |
The Staphylococcus-1 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] A Staphylococcus-1 motif RNAs is found in Staphylococcus species CAG-324, which has not yet (as of 2018) been more precisely classified. Other examples of Staphylococcus-1 RNAs are present in metagenomic sequences that do not correspond to a classified organism. It is assumed that the organism corresponding to these sequences are related to the Staphylococcus species.
Most Staphylococcus-1 RNAs are found in the apparent 5′ untranslated regions (5′ UTRs) of genes whose protein products exhibit a borderline similarity to HNH endonucleases. This genetic arrangement could suggest that Staphylococcus-1 RNAs function as cis-regulatory elements. However, one Staphylococcus-1 RNA is not located in a 5′ UTR calls this hypothesis into question, and suggests that the RNAs more likely function as small RNAs.
References
- ↑ "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. October 2017. doi:10.1093/nar/gkx699. PMID 28977401.
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