Biology:TLE4

From HandWiki
Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Transducin-like enhancer protein 4 is a protein that in humans is encoded by the TLE4 gene.[1][2]


Interactions

TLE4 has been shown to interact with PAX5.[3][4]

References

  1. "Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein". European Journal of Biochemistry 216 (1): 343–52. August 1993. doi:10.1111/j.1432-1033.1993.tb18151.x. PMID 8365415. 
  2. "Entrez Gene: TLE4 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)". https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=7091. 
  3. "Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family". The EMBO Journal 19 (10): 2292–303. May 2000. doi:10.1093/emboj/19.10.2292. PMID 10811620. 
  4. "A new Groucho TLE4 protein may regulate the repressive activity of Pax5 in human B lymphocytes". Immunology 106 (4): 447–55. August 2002. doi:10.1046/j.1365-2567.2002.01456.x. PMID 12153506. 

Further reading