Biology:TNFAIP1

From HandWiki
A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

BTB/POZ domain-containing protein TNFAIP1 is a protein that in humans is encoded by the TNFAIP1 gene.[1][2][3]

This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner.[3]

References

  1. "Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin". J Biol Chem 265 (5): 2973–8. Mar 1990. doi:10.1016/S0021-9258(19)39896-5. PMID 2406243. 
  2. "A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein". Mol Cell Biol 10 (11): 5830–8. Dec 1990. doi:10.1128/MCB.10.11.5830. PMID 2233719. 
  3. 3.0 3.1 "Entrez Gene: TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7126. 

Further reading