Biology:TWF2

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Twinfilin-2 is a protein that in humans is encoded by the TWF2 gene.[1][2][3]

The protein encoded by this gene was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin (PTK9), a conserved actin monomer-binding protein.[3]

References

  1. "Cloning, expression and characterization of an A6-related protein". Eur J Biochem 263 (2): 518–25. Aug 1999. doi:10.1046/j.1432-1327.1999.00537.x. PMID 10406962. 
  2. "Mammals have two twinfilin isoforms whose subcellular localizations and tissue distributions are differentially regulated". J Biol Chem 278 (36): 34347–55. Sep 2003. doi:10.1074/jbc.M303642200. PMID 12807912. 
  3. 3.0 3.1 "Entrez Gene: TWF2 twinfilin, actin-binding protein, homolog 2 (Drosophila)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11344. 

Further reading