Biology:Throat-1 RNA motif
From HandWiki
| throat-1 | |
|---|---|
 Consensus secondary structure and sequence conservation of throat-1 RNA | |
| Identifiers | |
| Symbol | throat-1 |
| Rfam | RF03110 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | 0001263 |
| PDB structures | PDBe |
The throat-1 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] The throat-1 motif has not yet (as of 2018) been found in a classified organism, but rather is known only from metagenomic sequences isolated from the human throat is, more rarely, tongue.
Throat-1 RNAs are only known within metagenomic sequences, and these sequences often consist of short contigs that do not permit detailed analysis of nearby protein-coding genes. However, even with this technical limitation, it is apparent that throat-1 RNAs do not have a strong association with neighboring genes. Therefore, they likely function in trans as small RNAs.
References
- ↑ "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. October 2017. doi:10.1093/nar/gkx699. PMID 28977401.
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