Biology:Tobamovirus internal ribosome entry site (IRES)
From HandWiki
The Tobamovirus internal ribosome entry site (IRES) is an element that allows cap and end-independent translation of mRNA in the host cell.[1] The IRES achieves this by mediating the internal initiation of translation by recruiting a ribosomal 43S pre-initiation complex directly to the initiation codon and eliminates the requirement for the eukaryotic initiation factor, eIF4F.[2]
See also
- Mnt IRES
- N-myc IRES
- TrkB IRES
References
- ↑ "A tobamovirus genome that contains an internal ribosome entry site functional in vitro". Virology 232 (1): 32–43. May 1997. doi:10.1006/viro.1997.8525. PMID 9185586.
- ↑ "Ribosomal binding to the internal ribosomal entry site of classical swine fever virus". RNA 6 (12): 1791–1807. December 2000. doi:10.1017/S1355838200000662. PMID 11142379.
External links
![]() | Original source: https://en.wikipedia.org/wiki/Tobamovirus internal ribosome entry site (IRES).
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