Biology:Trophinin

From HandWiki
Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Trophinin is a protein that in humans is encoded by the TRO gene.[1][2][3]

This gene encodes a membrane protein that mediates apical cell adhesion between trophoblastic cells and luminal epithelial cells of the endometrium and is implicated in the initial attachment during the process of embryo implantation. This gene is related to the MAGED gene family by sequence similarity and chromosome location. Multiple alternatively spliced transcript variants have been found for this gene; however, the full-length nature of some variants has not been defined.[3]

References

  1. "Assignment of trophoblast/endometrial epithelium cell adhesion molecule trophinin gene TRO to human chromosome bands Xp11.22→p11.21 by in situ hybridization". Cytogenet Cell Genet 79 (1–2): 123–4. Apr 1998. doi:10.1159/000134698. PMID 9533028. 
  2. "An overview of the MAGE gene family with the identification of all human members of the family". Cancer Res 61 (14): 5544–51. Jul 2001. PMID 11454705. 
  3. 3.0 3.1 "Entrez Gene: TRO trophinin". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7216. 

Further reading