Biology:Ultimopharyngeal body
| Ultimopharyngeal body | |
|---|---|
| Details | |
| Precursor | fourth pharyngeal pouch |
| Gives rise to | parafollicular cells |
| Identifiers | |
| Latin | corpus ultimopharyngeum |
| Anatomical terminology | |
The ultimopharyngeal body, or ultimobranchial body or ultimobranchial gland is a small organ found in the neck region of many animals. In humans, it develops from the fourth pharyngeal pouch into the parafollicular cells of the thyroid to produce calcitonin. It may not develop in DiGeorge syndrome.
Structure
The ultimopharyngeal body is a small organ of the neck. It is found in many animals. In humans, it develops into other tissues.
Development
In humans, the ultimopharyngeal body is an embryological structure, and is a derivative of the ventral recess of the fourth pharyngeal pouch.[1][2] It is technically from the fifth pharyngeal pouch, but this is rudimentary and merges with the fourth.[2] It develops into the parafollicular cells of the thyroid.[2] The cells that give rise to the parafollicular cells are derivatives of endoderm.[3] Endoderm cells migrate and associate with the ultimopharyngeal body during development.
Function
In humans, the ultimopharyngeal body develops into the parafollicular cells of the thyroid.[2] These secrete calcitonin.[4] In other animals, the ultimopharyngeal body may produce calcitonin.[4]
Clinical significance
The ultimopharyngeal body may not develop in DiGeorge syndrome.
History
The ultimopharyngeal body may also be known as the ultimobranchial body or the ultimobranchial gland.[2]
References
- ↑ "Ultimobranchial bodies" at Dorland's Medical Dictionary
- ↑ 2.0 2.1 2.2 2.3 2.4 "Branchial cleft anomalies: a pictorial review of embryological development and spectrum of imaging findings". Insights into Imaging 7 (1): 69–76. February 2016. doi:10.1007/s13244-015-0454-5. PMID 26661849.
- ↑ "Revising the embryonic origin of thyroid C cells in mice and humans". Development 142 (20): 3519–3528. October 2015. doi:10.1242/dev.126581. PMID 26395490.
- ↑ 4.0 4.1 "Calcitonin as an anticalcification treatment for implantable biological tissues". Journal of Cardiology. New insights in treatment for heart failure 73 (2): 179–182. February 2019. doi:10.1016/j.jjcc.2018.07.010. PMID 30377016.
External links
- ent/534 at eMedicine
- hednk-022—Embryo Images at University of North Carolina
 |  |
