Biology:Zinc finger protein 398

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Short description: Protein found in humans


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Zinc finger protein 398 is a protein that in humans is encoded by the ZNF398 gene.[1]

Function

This gene encodes a member of the Kruppel family of C2H2-type zinc-finger transcription factor proteins. The encoded protein acts as a transcriptional activator. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described, but their full length sequence has not been determined.

References

Further reading

  • "A novel zinc finger transcription factor with two isoforms that are differentially repressed by estrogen receptor-alpha". J. Biol. Chem. 277 (11): 9326–34. 2002. doi:10.1074/jbc.M107702200. PMID 11779858. 

This article incorporates text from the United States National Library of Medicine, which is in the public domain.