Chemistry:5-Chlorouracil

From HandWiki

5-Chlorouracil is an organochlorine compound that is a chlorinated version of the nucleobase uracil.[1] It is a marker for DNA damage caused by hypochlorous acid.[2] In vivo, it is converted into mutagenic chlorodeoxyuridine.[3]

See also

References

  1. ↑ PubChem. "5-Chlorouracil" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/15758. 
  2. ↑ Jiang, Qing; Blount, Ben C.; Ames, Bruce N. (2003-08-29). "5-Chlorouracil, a Marker of DNA Damage from Hypochlorous Acid during Inflammation: A GAS CHROMATOGRAPHY-MASS SPECTROMETRY ASSAY*". Journal of Biological Chemistry 278 (35): 32834–32840. doi:10.1074/jbc.M304021200. ISSN 0021-9258. PMID 12810714. 
  3. ↑ "5-Chlorouracil (CAS 1820-81-1)" (in en). https://www.caymanchem.com/product/27790/5-chlorouracil. 



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