Chemistry:Cephalotaxus alkaloids
From HandWiki
Cephalotaxus alkaloids are natural products characterized by pentacyclic structure.
Occurrence
These alkaloids are commonly found in the plum yew species (Cephalotaxus), especially in the Japanese plum-yew.[1]
Representative
The most important representative is cephalotaxin. Other notable representatives include harringtonine and homoharringtonine.[1]
Properties
Harringtonine and homoharringtonine exhibit antitumor activity and act against murine leukemia cells. They serve as protein and DNA biosynthesis inhibitors and are used against acute myelocytoxic leukemia.[1]
References
- ↑ 1.0 1.1 1.2 Entry on Cephalotaxus-Alkaloide. at: Römpp Online. Georg Thieme Verlag, retrieved {{{Datum}}}.
Original source: https://en.wikipedia.org/wiki/Cephalotaxus alkaloids.
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