Chemistry:Markush structure

From HandWiki
Short description: Chemical structure representation
Example of a Markush structure

History

Markush structures are named after Eugene A. Markush, founder of the Pharma Chemical Corporation in New Jersey. He was involved in a legal case that set a precedent for generic chemical structure patent filing, Ex parte Markush, 1925 Dec. Comm'r Pat. 126, 127 (1924).[1][2] The patent filing was US Application 611,637, filed January 9, 1923. Markush was awarded a patent from the US Patent Office for “Pyrazolone Dye and Process of Making the Same” on August 26, 1924.[3]

Use in patents

In describing a chemical, a Markush structure allows the patent-holder to list several active/effective structural formulas.

United States

In the United States, Markush structures are frequently used to claim alternative components. The correct format for a Markush structure is "closed."[4] In other words, the claim language defined by the Markush structure requires selection from a closed group.[5] One way of claiming a Markush structure follows the format: “a chemical selected from the group consisting of A, B, and C” where A, B, and C are alternative chemicals.[6]

A claimed Markush structure may be improper if (1) the members of the Markush structure do not share a "single structural similarity," or (2) if the members of the Markush structure do not share a common use.[7]

See also

References