Chemistry:Nelremagpran
From HandWiki
Nelremagpran is an experimental drug that acts as a potent and selective antagonist (or possibly inverse agonist) of the MAS-related Gq protein-coupled receptor X4 (MRGPRX4). It has antiinflammatory effects in animal studies. This receptor is poorly characterised but is thought to be involved in immune system function, and development of selective ligands is essential for researching its role in the body.[1][2]
References
- ↑ Yeager A, Selfridge B, Sainz M, Martinborough E, Boehm M, Huang, "Modulators of mas-related G-protein receptor x4 and related products and methods.", WO patent 2020/198537, published 1 October 2020
- ↑ "International Nonproprietary Names for Pharmaceutical Substances (INN).". WHO Drug Information 38 (4). 2024. https://cdn.who.int/media/docs/default-source/international-nonproprietary-names-(inn)/pl132.pdf.
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