Chemistry:Polychlorinated dibenzofurans

Short description: Family of organic compounds

More thorough treatise of all groups with similar actions and binding to aryl hydrocarbon receptor is given in Dioxins and dioxin-like compounds.

General chemical structure of PCDFs, where 2 ≤ n+m ≤ 8

Structures of the ten 2,3,7,8-substituted PCDF congeners that are toxicologically of most relevance

Polychlorinated dibenzofurans (PCDFs) are a family of organic compounds with one or several of the hydrogens in the dibenzofuran structure replaced by chlorines. For example, 2,3,7,8-tetrachlorodibenzofuran (TCDF) has chlorine atoms substituted for each of the hydrogens on the number 2, 3, 7, and 8 carbons (see structure in the upper left corner of the second image). Polychlorinated dibenzofurans with chlorines at least in positions 2,3,7 and 8 are much more toxic than the parent compound dibenzofurane, with properties and chemical structures similar to polychlorinated dibenzodioxins. These groups together are often inaccurately called dioxins. They are known developmental toxicants, and suspected human carcinogens. PCDFs tend to co-occur with polychlorinated dibenzodioxins (PCDDs). PCDFs can be formed by pyrolysis or incineration at temperatures below 1200 °C of chlorine containing products, such as PVC, PCBs, and other organochlorides, or of non-chlorine containing products in the presence of chlorine donors. Dibenzofurans are known persistent organic pollutants (POP), classified among the dirty dozen in the Stockholm Convention on Persistent Organic Pollutants.

Congeners

number	formula	name	CAS Number	InChIKey
PCDF-1	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_7\mathrm{C}\mathrm{l}\mathrm{O}$	1-chlorodibenzofuran	84761-86-4	WRSMJZYBNIAAEE-UHFFFAOYSA-N
PCDF-2	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_7\mathrm{C}\mathrm{l}\mathrm{O}$	2-chlorodibenzofuran	51230-49-0	PRKTYWJFCODJOA-UHFFFAOYSA-N
PCDF-3	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_7\mathrm{C}\mathrm{l}\mathrm{O}$	3-chlorodibenzofuran	25074-67-3	BBOZMMAURMEVAR-UHFFFAOYSA-N
PCDF-4	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_7\mathrm{C}\mathrm{l}\mathrm{O}$	4-chlorodibenzofuran	74992-96-4	RHRYBWFAHXCUCR-UHFFFAOYSA-N
PCDF-12	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	1,2-dichlorodibenzofuran	64126-85-8	QVAPRJWSOUITIF-UHFFFAOYSA-N
PCDF-13	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	1,3-dichlorodibenzofuran	94538-00-8	VKIBKEFGJSPRJC-UHFFFAOYSA-N
PCDF-14	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	1,4-dichlorodibenzofuran	94538-01-9	VHQCMZLPHWGUDB-UHFFFAOYSA-N
PCDF-16	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	1,6-dichlorodibenzofuran	74992-97-5	JRSRWACZUFLWKF-UHFFFAOYSA-N
PCDF-17	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	1,7-dichlorodibenzofuran	94538-02-0	XRQNHPGZRFKBJW-UHFFFAOYSA-N
PCDF-18	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	1,8-dichlorodibenzofuran	81638-37-1	UAFNQQBPUWFPGC-UHFFFAOYSA-N
PCDF-19	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	1,9-dichlorodibenzofuran	70648-14-5	AEKSGHBVWJHELW-UHFFFAOYSA-N
PCDF-23	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	2,3-dichlorodibenzofuran	64126-86-9	GETJJZZRPQFSFM-UHFFFAOYSA-N
PCDF-24	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	2,4-dichlorodibenzofuran	24478-74-8	LHTCKMYRNOGUOA-UHFFFAOYSA-N
PCDF-26	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	2,6-dichlorodibenzofuran	60390-27-4	XVLCNKFGFHUQNL-UHFFFAOYSA-N
PCDF-27	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	2,7-dichlorodibenzofuran	74992-98-6	DOZUTNBCPVUMPY-UHFFFAOYSA-N
PCDF-28	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	2,8-dichlorodibenzofuran	5409-83-6	IVVRJIDVYSPKFZ-UHFFFAOYSA-N
PCDF-34	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	3,4-dichlorodibenzofuran	94570-83-9	HYQGGNWDPQZLGX-UHFFFAOYSA-N
PCDF-36	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	3,6-dichlorodibenzofuran	74918-40-4	DMOBGFAKTSXOHG-UHFFFAOYSA-N
PCDF-37	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	3,7-dichlorodibenzofuran	58802-21-4	OLTYAGNRSNFHLK-UHFFFAOYSA-N
PCDF-46	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_6\mathrm{C}\mathrm{l}{\phantom{A}}_2\mathrm{O}$	4,6-dichlorodibenzofuran	64560-13-0	BZFIZJNKNCJEAD-UHFFFAOYSA-N
PCDF-123	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,2,3-trichlorodibenzofuran	83636-47-9	LADSWAAWPMGHBE-UHFFFAOYSA-N
PCDF-124	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,2,4-trichlorodibenzofuran	24478-73-7	RQIWKWHVZLDXEJ-UHFFFAOYSA-N
PCDF-126	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,2,6-trichlorodibenzofuran	64560-15-2	CYRZCBUWRUACKJ-UHFFFAOYSA-N
PCDF-127	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,2,7-trichlorodibenzofuran	83704-37-4	AFOVQGPNOZDUEP-UHFFFAOYSA-N
PCDF-128	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,2,8-trichlorodibenzofuran	83704-34-1	UYIGPSPCOXGBCS-UHFFFAOYSA-N
PCDF-129	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,2,9-trichlorodibenzofuran	83704-38-5	ICTXINQOXPMQPM-UHFFFAOYSA-N
PCDF-134	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,3,4-trichlorodibenzofuran	82911-61-3	FIPOITUDJFQRRN-UHFFFAOYSA-N
PCDF-136	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,3,6-trichlorodibenzofuran	83704-39-6	AGPTXRLVBIRYLV-UHFFFAOYSA-N
PCDF-137	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,3,7-trichlorodibenzofuran	64560-16-3	INRBXOGZPDFCLQ-UHFFFAOYSA-N
PCDF-138	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,3,8-trichlorodibenzofuran	76621-12-0	PHFSTDOPTZHECA-UHFFFAOYSA-N
PCDF-139	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,3,9-trichlorodibenzofuran	83704-40-9	SPPGDLROKBFNNO-UHFFFAOYSA-N
PCDF-146	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,4,6-trichlorodibenzofuran	82911-60-2	XDQRWSUJOURTHK-UHFFFAOYSA-N
PCDF-147	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,4,7-trichlorodibenzofuran	83704-41-0	XTLMVJUSIANHND-UHFFFAOYSA-N
PCDF-148	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,4,8-trichlorodibenzofuran	64560-14-1	PCQCYDNFBUADOK-UHFFFAOYSA-N
PCDF-149	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,4,9-trichlorodibenzofuran	70648-13-4	NVYUPBVXKLTYHV-UHFFFAOYSA-N
PCDF-167 (PCDF-349)	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,6,7-trichlorodibenzofuran	83704-46-5	HEWLCNCSWBMZHG-UHFFFAOYSA-N
PCDF-168 (PCDF-249)	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,6,8-trichlorodibenzofuran	82911-59-9	ZOBVYDQWZXUJNO-UHFFFAOYSA-N
PCDF-178 (PCDF-239)	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	1,7,8-trichlorodibenzofuran	58802-18-9	YNMCXGLWHTVMQO-UHFFFAOYSA-N
PCDF-234	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	2,3,4-trichlorodibenzofuran	57117-34-7	YDLADWPBKZODCJ-UHFFFAOYSA-N
PCDF-236	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	2,3,6-trichlorodibenzofuran	57117-33-6	CPMGJTLNRBIKQM-UHFFFAOYSA-N
PCDF-237	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	2,3,7-trichlorodibenzofuran	58802-17-8	CKXMNTLGGAOERF-UHFFFAOYSA-N
PCDF-238	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	2,3,8-trichlorodibenzofuran	57117-32-5	NUNSNNOYACKRIK-UHFFFAOYSA-N
PCDF-246	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	2,4,6-trichlorodibenzofuran	58802-14-5	GTKURBTWZFQHHY-UHFFFAOYSA-N
PCDF-247	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	2,4,7-trichlorodibenzofuran	83704-42-1	SZBZRVJHPZIGAY-UHFFFAOYSA-N
PCDF-248	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	2,4,8-trichlorodibenzofuran	54589-71-8	WJURXKWTCOMRCE-UHFFFAOYSA-N
PCDF-346	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	3,4,6-trichlorodibenzofuran	83704-43-2	XEUHBCMRIXEBTD-UHFFFAOYSA-N
PCDF-347	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	3,4,7-trichlorodibenzofuran	83704-44-3	RPJJBTSXPNFUTA-UHFFFAOYSA-N
PCDF-348	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_5\mathrm{C}\mathrm{l}{\phantom{A}}_3\mathrm{O}$	3,4,8-trichlorodibenzofuran	83704-45-4	YTZWNIQGGIJHJX-UHFFFAOYSA-N
PCDF-1234	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,3,4-tetrachlorodibenzofuran	24478-72-6	AETAPIFVELRIDN-UHFFFAOYSA-N
PCDF-1236	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,3,6-tetrachlorodibenzofuran	83704-21-6	BBAXFLIBRPXRBP-UHFFFAOYSA-N
PCDF-1237	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,3,7-tetrachlorodibenzofuran	83704-22-7	MDNZFYGATDCKRB-UHFFFAOYSA-N
PCDF-1238	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,3,8-tetrachlorodibenzofuran	62615-08-1	KFQRHGKKSHJMCO-UHFFFAOYSA-N
PCDF-1239	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,3,9-tetrachlorodibenzofuran	83704-23-8	GNQHLJHTOATTOJ-UHFFFAOYSA-N
PCDF-1246	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,4,6-tetrachlorodibenzofuran	71998-73-7	NLVWEKPJFUPVMZ-UHFFFAOYSA-N
PCDF-1247	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,4,7-tetrachlorodibenzofuran	83719-40-8	MFURKMJLDQBHRA-UHFFFAOYSA-N
PCDF-1248	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,4,8-tetrachlorodibenzofuran	64126-87-0	BFTASCFRRBHFFK-UHFFFAOYSA-N
PCDF-1249	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,4,9-tetrachlorodibenzofuran	83704-24-9	ZUYYTCCHKQGGOV-UHFFFAOYSA-N
PCDF-1267	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,6,7-tetrachlorodibenzofuran	83704-25-0	AUEWYHHKDYUYMI-UHFFFAOYSA-N
PCDF-1268	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,6,8-tetrachlorodibenzofuran	83710-07-0	KCVGVSIBBGIJNZ-UHFFFAOYSA-N
PCDF-1269	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,6,9-tetrachlorodibenzofuran	70648-18-9	IEPGLLVEBKXASE-UHFFFAOYSA-N
PCDF-1278	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,7,8-tetrachlorodibenzofuran	58802-20-3	JODWPAQNABOHDG-UHFFFAOYSA-N
PCDF-1279	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,7,9-tetrachlorodibenzofuran	83704-26-1	PDMFRPIFZAKMLH-UHFFFAOYSA-N
PCDF-1289	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,2,8,9-tetrachlorodibenzofuran	70648-22-5	OHYCQUKMNPHFPT-UHFFFAOYSA-N
PCDF-1346	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,3,4,6-tetrachlorodibenzofuran	83704-27-2	CBBDONKZEJKFJP-UHFFFAOYSA-N
PCDF-1347	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,3,4,7-tetrachlorodibenzofuran	70648-16-7	UMKCVDZTSZNWRH-UHFFFAOYSA-N
PCDF-1348	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,3,4,8-tetrachlorodibenzofuran	92341-04-3	XWKRJSMNDOXIHS-UHFFFAOYSA-N
PCDF-1349	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,3,4,9-tetrachlorodibenzofuran	83704-28-3	PNCYJHOTZSKZPA-UHFFFAOYSA-N
PCDF-1367	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,3,6,7-tetrachlorodibenzofuran	57117-36-9	PITDPGCTIMCYEZ-UHFFFAOYSA-N
PCDF-1368	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,3,6,8-tetrachlorodibenzofuran	71998-72-6	BDXKVABZWRZKOS-UHFFFAOYSA-N
PCDF-1369	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,3,6,9-tetrachlorodibenzofuran	83690-98-6	NJQQZRLWVLWNGD-UHFFFAOYSA-N
PCDF-1378	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,3,7,8-tetrachlorodibenzofuran	57117-35-8	CSXDVUGDFSYXTD-UHFFFAOYSA-N
PCDF-1379	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,3,7,9-tetrachlorodibenzofuran	64560-17-4	IEMJMCVYAORWJV-UHFFFAOYSA-N
PCDF-1467	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,4,6,7-tetrachlorodibenzofuran	66794-59-0	RBFNYMHNIOKXLA-UHFFFAOYSA-N
PCDF-1468	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,4,6,8-tetrachlorodibenzofuran	82911-58-8	VHOBVPNETFRJED-UHFFFAOYSA-N
PCDF-1469	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,4,6,9-tetrachlorodibenzofuran	70648-19-0	JAYSBJFHDJOMGZ-UHFFFAOYSA-N
PCDF-1478	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,4,7,8-tetrachlorodibenzofuran	83704-29-4	IVRDRRWQABCXLY-UHFFFAOYSA-N
PCDF-1678	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	1,6,7,8-tetrachlorodibenzofuran	83704-33-0	KOJMOXYETDLOPN-UHFFFAOYSA-N
PCDF-2346	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	2,3,4,6-tetrachlorodibenzofuran	83704-30-7	JNVHSHPAAMRSKK-UHFFFAOYSA-N
PCDF-2347	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	2,3,4,7-tetrachlorodibenzofuran	83704-31-8	BROFYOSLFHTGCQ-UHFFFAOYSA-N
PCDF-2348	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	2,3,4,8-tetrachlorodibenzofuran	83704-32-9	IIKXRERKNIJJQY-UHFFFAOYSA-N
PCDF-2367	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	2,3,6,7-tetrachlorodibenzofuran	57117-39-2	MJCNKMDTLRSHNK-UHFFFAOYSA-N
PCDF-2368	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	2,3,6,8-tetrachlorodibenzofuran	57117-37-0	SPMZHWVRMWWTSY-UHFFFAOYSA-N
PCDF-2378	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	2,3,7,8-tetrachlorodibenzofuran	51207-31-9	KSMVNVHUTQZITP-UHFFFAOYSA-N
PCDF-2467	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	2,4,6,7-tetrachlorodibenzofuran	57117-38-1	NSDXKMRVQOSASS-UHFFFAOYSA-N
PCDF-2468	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	2,4,6,8-tetrachlorodibenzofuran	58802-19-0	ZSPJEACWUWSAGS-UHFFFAOYSA-N
PCDF-3467	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_4\mathrm{C}\mathrm{l}{\phantom{A}}_4\mathrm{O}$	3,4,6,7-tetrachlorodibenzofuran	57117-40-5	LMJLCLBSUNZLNW-UHFFFAOYSA-N
PCDF-12346	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,3,4,6-pentachlorodibenzofuran	83704-47-6	LIQJBAPSLUZUTB-UHFFFAOYSA-N
PCDF-12347	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,3,4,7-pentachlorodibenzofuran	83704-48-7	DOJZTBGOWIYFAC-UHFFFAOYSA-N
PCDF-12348	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,3,4,8-pentachlorodibenzofuran	67517-48-0	ZCTNDJSCLPJCRA-UHFFFAOYSA-N
PCDF-12349	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,3,4,9-pentachlorodibenzofuran	83704-49-8	IQSZNZVZXOFRJS-UHFFFAOYSA-N
PCDF-12367	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,3,6,7-pentachlorodibenzofuran	57117-42-7	NZUPQBVDIWCPBX-UHFFFAOYSA-N
PCDF-12368	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,3,6,8-pentachlorodibenzofuran	83704-51-2	VHQJZOFUPXEZQZ-UHFFFAOYSA-N
PCDF-12369	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,3,6,9-pentachlorodibenzofuran	83704-52-3	IPSFQAKXDJVQOX-UHFFFAOYSA-N
PCDF-12378	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,3,7,8-pentachlorodibenzofuran	57117-41-6	SBMIVUVRFPGOEB-UHFFFAOYSA-N
PCDF-12379	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,3,7,9-pentachlorodibenzofuran	83704-53-4	JVUSEQPOWCBYNG-UHFFFAOYSA-N
PCDF-12389	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,3,8,9-pentachlorodibenzofuran	83704-54-5	NKGLWUJPCTUDEH-UHFFFAOYSA-N
PCDF-12467	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,4,6,7-pentachlorodibenzofuran	83704-50-1	BQTCODOVGXJHRB-UHFFFAOYSA-N
PCDF-12468	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,4,6,8-pentachlorodibenzofuran	69698-57-3	JDTUAYPJSSXDNO-UHFFFAOYSA-N
PCDF-12469	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,4,6,9-pentachlorodibenzofuran	70648-24-7	QDQFGVXGPSYEJU-UHFFFAOYSA-N
PCDF-12478	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,4,7,8-pentachlorodibenzofuran	58802-15-6	GCFDWHIKRXCUPJ-UHFFFAOYSA-N
PCDF-12479	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,4,7,9-pentachlorodibenzofuran	71998-74-8	IYGVHNHWORPMFU-UHFFFAOYSA-N
PCDF-12489	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,4,8,9-pentachlorodibenzofuran	70648-23-6	ZSPAPWGNAGTCCA-UHFFFAOYSA-N
PCDF-12678 (PCDF-23489)	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,6,7,8-pentachlorodibenzofuran	69433-00-7	ZAAVDGLJEOXCMV-UHFFFAOYSA-N
PCDF-12679	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,2,6,7,9-pentachlorodibenzofuran	70872-82-1	QQRRQEVOSMEVQB-UHFFFAOYSA-N
PCDF-13467	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,3,4,6,7-pentachlorodibenzofuran	83704-36-3	JVYYDUWJIJMOGW-UHFFFAOYSA-N
PCDF-13468	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,3,4,6,8-pentachlorodibenzofuran	83704-55-6	COKIAYPRHYHYCH-UHFFFAOYSA-N
PCDF-13469	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,3,4,6,9-pentachlorodibenzofuran	70648-15-6	MYSAFUYQSBEEDR-UHFFFAOYSA-N
PCDF-13478	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,3,4,7,8-pentachlorodibenzofuran	58802-16-7	ORSUQGVCWLXKLZ-UHFFFAOYSA-N
PCDF-13479	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,3,4,7,9-pentachlorodibenzofuran	70648-20-3	GFXPLABVZOBCCW-UHFFFAOYSA-N
PCDF-13678	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,3,6,7,8-pentachlorodibenzofuran	70648-21-4	FRLMQDUYUJIHCZ-UHFFFAOYSA-N
PCDF-14678	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	1,4,6,7,8-pentachlorodibenzofuran	83704-35-2	VANGHZRYKXDPRR-UHFFFAOYSA-N
PCDF-23467	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	2,3,4,6,7-pentachlorodibenzofuran	57117-43-8	SJFBZRQKGOGHEV-UHFFFAOYSA-N
PCDF-23468	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	2,3,4,6,8-pentachlorodibenzofuran	67481-22-5	MKRFORPSRBMAIP-UHFFFAOYSA-N
PCDF-23478	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_3\mathrm{C}\mathrm{l}{\phantom{A}}_5\mathrm{O}$	2,3,4,7,8-pentachlorodibenzofuran	57117-31-4	OGBQILNBLMPPDP-UHFFFAOYSA-N
PCDF-123467	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,2,3,4,6,7-hexachlorodibenzofuran	79060-60-9	SNWFMKXFMVHBKD-UHFFFAOYSA-N
PCDF-123468	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,2,3,4,6,8-hexachlorodibenzofuran	69698-60-8	UCFGNWHERVQWMZ-UHFFFAOYSA-N
PCDF-123469	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,2,3,4,6,9-hexachlorodibenzofuran	91538-83-9	KFFUZIROJGXTQH-UHFFFAOYSA-N
PCDF-123478	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,2,3,4,7,8-hexachlorodibenzofuran	70648-26-9	LVYBAQIVPKCOEE-UHFFFAOYSA-N
PCDF-123479	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,2,3,4,7,9-hexachlorodibenzofuran	91538-84-0	BKIXWRBZCQEZAQ-UHFFFAOYSA-N
PCDF-123489	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,2,3,4,8,9-hexachlorodibenzofuran	92341-07-6	VSDUQUBUJRNREH-UHFFFAOYSA-N
PCDF-123678	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,2,3,6,7,8-hexachlorodibenzofuran	57117-44-9	JEYJJJXOFWNEHN-UHFFFAOYSA-N
PCDF-123679	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,2,3,6,7,9-hexachlorodibenzofuran	92341-06-5	JZVOLXQREJNTTL-UHFFFAOYSA-N
PCDF-123689	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,2,3,6,8,9-hexachlorodibenzofuran	75198-38-8	WLGQZUOHEXTWFH-UHFFFAOYSA-N
PCDF-123789	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,2,3,7,8,9-hexachlorodibenzofuran	72918-21-9	PYUSJFJVDVSXIU-UHFFFAOYSA-N
PCDF-124678	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,2,4,6,7,8-hexachlorodibenzofuran	67562-40-7	CKDDYGBBKXIHRY-UHFFFAOYSA-N
PCDF-124679	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,2,4,6,7,9-hexachlorodibenzofuran	75627-02-0	FAHIPPHRJJJQOG-UHFFFAOYSA-N
PCDF-124689	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,2,4,6,8,9-hexachlorodibenzofuran	69698-59-5	FGZCXIPKUCJGHW-UHFFFAOYSA-N
PCDF-134678	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,3,4,6,7,8-hexachlorodibenzofuran	71998-75-9	OGTZINCGZYXZCR-UHFFFAOYSA-N
PCDF-134679	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	1,3,4,6,7,9-hexachlorodibenzofuran	92341-05-4	TURXXOIFVABBPW-UHFFFAOYSA-N
PCDF-234678	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}{\phantom{A}}_2\mathrm{C}\mathrm{l}{\phantom{A}}_6\mathrm{O}$	2,3,4,6,7,8-hexachlorodibenzofuran	60851-34-5	XTAHLACQOVXINQ-UHFFFAOYSA-N
PCDF-1234678	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}\mathrm{C}\mathrm{l}{\phantom{A}}_7\mathrm{O}$	1,2,3,4,6,7,8-heptachlorodibenzofuran	67562-39-4	WDMKCPIVJOGHBF-UHFFFAOYSA-N
PCDF-1234679	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}\mathrm{C}\mathrm{l}{\phantom{A}}_7\mathrm{O}$	1,2,3,4,6,7,9-heptachlorodibenzofuran	70648-25-8	JWXWOEUKHXOUSK-UHFFFAOYSA-N
PCDF-1234689	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}\mathrm{C}\mathrm{l}{\phantom{A}}_7\mathrm{O}$	1,2,3,4,6,8,9-heptachlorodibenzofuran	69698-58-4	BADFHCOLISGRRW-UHFFFAOYSA-N
PCDF-1234789	$\mathrm{C}{\phantom{A}}_{12}\mathrm{H}\mathrm{C}\mathrm{l}{\phantom{A}}_7\mathrm{O}$	1,2,3,4,7,8,9-heptachlorodibenzofuran	55673-89-7	VEZCTZWLJYWARH-UHFFFAOYSA-N
PCDF-12346789	$\mathrm{C}{\phantom{A}}_{12}\mathrm{C}\mathrm{l}{\phantom{A}}_8\mathrm{O}$	octachlorodibenzofuran	39001-02-0	RHIROFAGUQOFLU-UHFFFAOYSA-N

Safety, toxicity, regulation

Occupational exposure to PCDFs may occur through inhalation and contact with the skin, although intake even in workers at waste incineration plants is not particularly high. For general population the most important source is food of animal origin like with other dioxin-like compounds. The most relevant congener is 2,3,4,7,8-pentachlorodibenzofuran (2,3,4,7,8-PCDF) which is more toxic and based on relative toxicity more prevalent than other PCDFs.

See also

• Dioxins and dioxin-like compounds
• Polychlorinated biphenyl

Further resources

• Synopsis on dioxins and PCBs
• Chemical Profile: DIBENZOFURANS (CHLORINATED)
• NPI Polychlorinated dioxins and furans fact sheet