Chemistry:Psychedelic microdosing

From HandWiki
Short description: Drug experimentation technique


Psychedelic microdosing involves consuming sub-threshold doses (microdoses) of serotonergic psychedelic drugs like LSD and psilocybin to potentially enhance creativity, energy, emotional balance, problem-solving abilities, and to address anxiety, depression, and addiction.[1][2] This practice has gained popularity in the 21st century.[3][4]

Techniques

Microdosing typically involves 1/20 to 1/10 of a recreational dose of psychedelics like LSD.[5]

LSD and psilocybin are the most commonly used substances for microdosing, with volumetric liquid dosing often employed for precise LSD measurement.[5][6] A microdose is usually 1/20 to 1/10 of an active dose of a psychedelic drug.[5][7]

Prevalence and demographics

Gender and education significantly influence microdosing prevalence. An online survey revealed that 13% of 2,437 respondents had practiced microdosing, with current microdosers at 4%.[8] Microdosers typically have lower incomes and education levels, with no specific employment type associated.[8]

A separate survey of Reddit users found no significant difference in age, sexual orientation, social class, or education level between microdosers and non-microdosers. However, microdosers were more likely to be male, less religious, and reported a lower incidence of anxiety or substance use disorders. They commonly used LSD or psilocybin on a one-day-on, two-days-off schedule.[9]

See also

References

  1. "Microdose research: without approvals, control groups, double blinds, staff or funding". Psychedelic Press XV. January 2016. https://www.researchgate.net/publication/308138461. 
  2. "The truth about 'microdosing,' which involves taking tiny amounts of psychedelics like LSD". Business Insider. 30 January 2017. http://www.businessinsider.com/microdosing-lsd-effects-risks-2017-1. 
  3. "A Brief History of LSD in the Twenty-First Century". Psychedelic Press UK. 7 July 2015. http://psypressuk.com/2015/07/07/a-brief-history-of-lsd-in-the-twenty-first-century/. 
  4. Ellwood, Beth (2020-10-28). "International study finds 79% of individuals who microdose with psychedelics report improvements in their mental health" (in en-US). https://www.psypost.org/2020/10/international-study-finds-79-of-individuals-who-microdose-with-psychedelics-report-improvements-in-their-mental-health-58391. 
  5. 5.0 5.1 5.2 "A systematic study of microdosing psychedelics". PLOS ONE 14 (2): e0211023. 2019-02-06. doi:10.1371/journal.pone.0211023. PMID 30726251. Bibcode2019PLoSO..1411023P. 
  6. "The Effects of Low Doses of Lysergic Acid Diethylamide in Healthy Humans: Demystifying the Microdosing of Psychedelics". Biological Psychiatry 86 (10): 736–737. November 2019. doi:10.1016/j.biopsych.2019.08.021. PMID 31648681. 
  7. "The therapeutic potential of microdosing psychedelics in depression". Therapeutic Advances in Psychopharmacology 10: 1–2. 2020-01-01. doi:10.1177/2045125320950567. PMID 32922736. 
  8. 8.0 8.1 "Psychedelic Microdosing: Prevalence and Subjective Effects". Journal of Psychoactive Drugs 52 (2): 113–122. January 2020. doi:10.1080/02791072.2020.1718250. PMID 31973684. 
  9. "Microdosing psychedelics: Demographics, practices, and psychiatric comorbidities" (in en-US). Journal of Psychopharmacology 34 (6): 612–622. June 2020. doi:10.1177/0269881120908004. PMID 32108529.