Chemistry:Sulopenem
From HandWiki
Short description: Chemical compound
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| Formula | C12H15NO5S3 |
| Molar mass | 349.43 g·mol−1 |
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Sulopenem (CP-70,429) is an antibiotic derivative from the carbapenem family, which unlike most related drugs is orally active. It was developed in Japan in the 1990s but has never been approved for medical use, however it has reached Phase III clinical trials on several occasions and continues to be the subject of ongoing research into potential applications, especially in the treatment of multiple drug resistant urinary tract infections.[1][2][3][4][5]
See also
References
- ↑ "In vitro antibacterial activity and beta-lactamase stability of CP-70,429 a new penem antibiotic". Antimicrobial Agents and Chemotherapy 37 (7): 1547–1551. July 1993. doi:10.1128/AAC.37.7.1547. PMID 8363389.
- ↑ "Chemical and microbiologic aspects of penems, a distinct class of beta-lactams: focus on faropenem". Pharmacotherapy 23 (11): 1497–1507. November 2003. doi:10.1592/phco.23.14.1497.31937. PMID 14620395.
- ↑ "Antianaerobic activity of sulopenem compared to six other agents". Antimicrobial Agents and Chemotherapy 53 (5): 2163–2170. May 2009. doi:10.1128/AAC.01557-08. PMID 19223615.
- ↑ "Treatment of urinary tract infections in the era of antimicrobial resistance and new antimicrobial agents". Postgraduate Medicine 132 (3): 234–250. April 2020. doi:10.1080/00325481.2019.1680052. PMID 31608743.
- ↑ "Oral Antibiotics in Clinical Development for Community-Acquired Urinary Tract Infections". Infectious Diseases and Therapy 10 (4): 1815–1835. December 2021. doi:10.1007/s40121-021-00509-4. PMID 34357517.
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