Chemistry:Vioxanthin

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Vioxanthin is a mycotoxin that was first isolated from the pathogenic fungus Trichophyton violaceum and characterized in 1966.[1] It is a pigment with a brownish-yellow color.[1] It has since been found to be a constituent of a variety of other fungi including those in the genus Penicillium[2] and Aspergillus.[3] The detection of vioxanthin in food products has been used as evidence of contamination with these fungi.[4]

A laboratory synthesis of vioxanthin has been reported.[5]

References

  1. 1.0 1.1 Blank, F.; Ng, A. S.; Just, G. (1966). "Metabolites of Pathogenic Fungi: V. Isolation and Tentative Structures of Vioxanthin and Viopurpurin, Two Colored Metabolites of Trichophyton Violaceum". Canadian Journal of Chemistry 44 (23): 2873–2879. doi:10.1139/v66-427. https://cdnsciencepub.com/doi/pdf/10.1139/v66-427. 
  2. Scudamore, K. A.; Clarke, J. H.; Hetmanski, M. T. (1993). "Isolation of Penicillium strains producing ochratoxin A, citrinin, xanthomegnin, viomellein and vioxanthin from stored cereal grains". Letters in Applied Microbiology 17 (2): 82–87. doi:10.1111/j.1472-765X.1993.tb00377.x. 
  3. Stack, Michael E.; Mislivec, Philip B.; Denizel, Turgut; Gibson, Regina; Pohland, Albert E. (1983). "Ochratoxins a and B, Xanthomegnin, Viomellein and Vioxanthin Production by Isolates of Aspergillus ochraceus from Green Coffee Beans". Journal of Food Protection 46 (11): 965–968. doi:10.4315/0362-028X-46.11.965. PMID 30921851. 
  4. Scudamore, Keith A.; Atkin, Pauline M.; Buckle, Anthony E. (1986). "Natural occurrence of the naphthoquinone mycotoxins, xanthomegnin, viomellein and vioxanthin in cereals and animal feldstuffs". Journal of Stored Products Research 22 (2): 81–84. doi:10.1016/0022-474X(86)90023-8. 
  5. Bode, Silke E.; Drochner, Daniel; Müller, Michael (2007). "Synthesis, Biosynthesis, and Absolute Configuration of Vioxanthin". Angewandte Chemie International Edition 46 (31): 5916–5920. doi:10.1002/anie.200701014. PMID 17607794. Bibcode2007ACIE...46.5916B.