Company:Mapp Biopharmaceutical
Key people | President: Larry Zeitlin, CEO: Kevin Whaley[1] |
|---|---|
| Products | Biopharmaceuticals |
| Subsidiaries | LeafBio |
Mapp Biopharmaceutical is an American pharmaceutical company based in San Diego, California . It is responsible for the research and development of ZMapp, a drug which is still under development, comprising three humanized monoclonal antibodies as a treatment for Ebola virus disease.[2][3] The drug was first tested in humans during the 2014 West Africa Ebola virus outbreak. The ZMapp drug is a result of the collaboration between Mapp Biopharmaceutical, LeafBio (the commercial arm of Mapp Biopharmaceutical),[4] Defyrus Inc. (Toronto), the U.S. government and the Public Health Agency of Canada.[2] The antibody work came out of research projects funded by Defense Advanced Research Projects Agency (DARPA) more than a decade ago,[5] and years of funding by the Public Health Agency of Canada.[6] ZMapp is manufactured in the tobacco plant Nicotiana benthamiana in the bioproduction process known as "pharming" by Kentucky BioProcessing, a subsidiary of Reynolds American.[7][8][9]
References
- ↑ "Ebola Drug Made From Tobacco Plant Saves U.S. Aid Workers". Bloomberg. August 5, 2014Add. https://www.bloomberg.com/news/2014-08-05/ebola-drug-made-from-tobacco-plant-saves-u-s-aid-workers.html.
- ↑ 2.0 2.1 "ZMapp Information Sheet". Mapp Biopharmaceutical. Archived from the original on 2014-08-12. https://web.archive.org/web/20140812212046/http://www.mappbio.com/zmapinfo.pdf.
- ↑ "Mystery Ebola virus serum manufactured by San Diego firm". Los Angeles Times. August 4, 2014.
- ↑ "LeafBio". http://www.leafbio.com/. Retrieved August 12, 2014.
- ↑ "Ebola Drug Made From Tobacco Plant Saves U.S. Aid Workers". BusinessWeek. August 4, 2014. http://www.businessweek.com/news/2014-08-04/ebola-drug-made-from-tobacco-plant-saves-u-dot-s-dot-aid-workers.
- ↑ Helen Branswell for The Canadian Press. Aug. 5, 2014 Experimental Ebola drug based on research discoveries from Canada's national lab
- ↑ Kroll, David (5 August 2014). "Ebola 'Secret Serum': Small Biopharma, The Army, And Big Tobacco". Forbes. https://www.forbes.com/sites/davidkroll/2014/08/05/ebola-secret-serum-small-biopharma-the-army-and-big-tobacco/.
- ↑ Parshley, Lois (8 August 2014). "ZMapp: The Experimental Ebola Treatment Explained". Popular Science. http://www.popsci.com/article/science/zmapp-experimental-ebola-treatment-explained.
- ↑ Daniel, Fran (12 August 2014). "Ebola drug provided for two Americans by Reynolds American subsidiary". Winston-Salem Journal. http://www.journalnow.com/news/local/ebola-drug-provided-for-two-americans-by-reynolds-american-subsidiary/article_144fb3ce-1cb3-11e4-9f1b-0017a43b2370.html.
External links
- Website of Mapp Biopharmaceutical
- Longtime vision leads to Ebola serum (Interview with Larry Zeitlin, August 6, 2014)
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