Medicine:Clichy criteria

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Short description: Proposed criteria to determine Acute liver failure

The Clichy criteria are a group of criteria proposed in determining the survival of individuals with acute liver failure. It was based on a study of patients presenting with viral hepatitis, of which individuals with the lowest survival were identified.

Two criteria predicted the prognosis of patients with poor survival:

  • Factor V level less than 20 percent of its normal value in individuals less than thirty years of age
  • Factor V level less than 30 percent of its normal value in individuals greater than thirty years of age.

The positive predictive value of mortality was 82% and the negative predictive value of mortality was 98% in individuals meeting these criteria.

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