Medicine:Ladin's sign
Ladin's sign is a clinical sign of pregnancy in which there is softening in the midline of the uterus anteriorly at the junction of the uterus and cervix. It occurs and is detectable with a manual examination at about 6 weeks' gestation.[1] Ladin's sign is often present during the woman's first pelvic exam when pregnancy is suspected.[2] Cervical length is also significant in pregnancy and shorter or shortening length can increase chances of preterm labour and delivery as this shortening happens naturally at the beginning of labour.[3] The cervix softens from conception and combined with other signs of early pregnancy, detecting Ladin's sign can assist clinicians in verifying a diagnosis of pregnancy.[4] Abnormal softening of the cervix can also occur in pregnancy, so testing for abnormalities of uterine cervical softening, including sheer wave speed measurement, can be used as a method of distinguishing between normal and abnormal softening.[5]
See also
- Chadwick sign
- Goodell's sign
- Hegar sign
References
- ↑ Alan H. DeCherney, Martin L. Pernoll, Lauren Nathan. Current Obstetric & Gynecologic Diagnosis & Treatment, page 196. McGraw-Hill Professional, 2002. ISBN:978-0-8385-1401-6. Google books
- ↑ Clinical examination of pregnant women. National Collaborating Centre for Women's and Children's Health. March 2008. https://www.ncbi.nlm.nih.gov/books/NBK51890/.
- ↑ "Cervical length: Why does it matter during pregnancy? - Mayo Clinic" (in en). https://www.mayoclinic.org/healthy-lifestyle/pregnancy-week-by-week/expert-answers/cervical-length/faq-20058357?p=1.
- ↑ "Cervical softening occurs early in pregnancy: characterization of cervical stiffness in 100 healthy women using the aspiration technique". Prenatal Diagnosis 33 (8): 737–41. August 2013. doi:10.1002/pd.4116. PMID 23553612.
- ↑ "Quantitative assessment of cervical softening during pregnancy in the Rhesus macaque with shear wave elasticity imaging". Physics in Medicine and Biology 63 (8): 085016. April 2018. doi:10.1088/1361-6560/aab532. PMID 29517492. Bibcode: 2018PMB....63h5016R.
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