Medicine:Therapeutic Lifestyle Change (depression treatment)

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Therapeutic Lifestyle Change (TLC) is a treatment for depression which was developed by Dr. Stephen Ilardi and several graduate students[1] at the University of Kansas.[2] The TLC program is drug-free and relies on six lifestyle changes. The program has been found to be an effective treatment for depression, with 70[3]-75%[4] of patients experiencing a significant reduction in depressive symptoms.

Background

The World Health Organisation has stated that depression is a leading cause of disability worldwide and a major contributor to the global burden of disease.[5] Stephen Ilardi has described depression as a "disease of civilisation", stating "We were never designed for the sedentary, indoor, sleep-deprived, socially-isolated, fast-food-laden, frenetic pace of modern life".[2]

Ilardi has stated that the increasing prevalence of depression is largely due to unhealthy lifestyle choices, particularly among people in developed nations. He cites research which has established that the prevalence of depression is significantly lower in parts of the world where people still live traditional lifestyles.[6]

TLC components

The TLC is composed of six lifestyle changes which include:[6]

Efficacy

In his book The Depression Cure: The 6-Step Program to Beat Depression without Drugs, Ilardi cites a 2002 meta-analysis by Kirsh,[7] which found that roughly half of depressed patients[8] will not experience a meaningful reduction in depressive symptoms after using antidepressants. In comparison, 70[3]-75%[4] of patients who were treated with the TLC program noticed a significant reduction in depressive symptoms (indicated by an at least 50% reduction in symptoms).

References

  1. Ilardi, Stephen (2009). The Depression Cure: The 6-Step Program to Beat Depression without Drugs. Da Capo Lifelong Books. pp. vii (Introduction). ISBN 9780738213132. 
  2. 2.0 2.1 "TLC Home" (in en). 2015-04-28. http://tlc.ku.edu/tlc-home. 
  3. 3.0 3.1 "TLC Home" (in en). 2015-04-28. http://tlc.ku.edu/tlc-home. "Our research has demonstrated that TLC is an effective treatment for depression, with over 70% of patients experiencing a favorable response, as measured by symptom reduction of at least 50%." 
  4. 4.0 4.1 Ilardi, Stephen (2009). The Depression Cure: The 6-Step Program to Beat Depression without Drugs. Cambridge, Massachusetts: Da Capo Lifelong Books. pp. viii (Introduction). ISBN 9780738213132. "But the response rate among TLC patients was over three times higher (Compared to medication, where only 25% of patients experienced a significant reduction in depressive symptoms)" 
  5. "Depression" (in en). https://www.who.int/news-room/fact-sheets/detail/depression. 
  6. 6.0 6.1 (in en) Depression is a disease of civilization: Stephen Ilardi at TEDxEmory, https://www.youtube.com/watch?v=drv3BP0Fdi8, retrieved 2023-03-16 
  7. Kirsch, Irving; Moore, Thomas J.; Scoboria, Alan; Nicholls, Sarah S. (15 July 2002). "The emperor's new drugs: An analysis of antidepressant medication data submitted to the U.S. Food and Drug Administration." (in en). Prevention & Treatment 5 (1). doi:10.1037/1522-3736.5.1.523a. ISSN 1522-3736. http://doi.apa.org/getdoi.cfm?doi=10.1037/1522-3736.5.1.523a. 
  8. Simons, Jake Wallis (2010-07-19). "How to beat depression – without drugs" (in en-GB). The Guardian. ISSN 0261-3077. https://www.theguardian.com/lifeandstyle/2010/jul/19/beat-depression-without-drugs. ""Meds have only around a 50% success rate", he says. "Moreover, of the people who do improve, half experience a relapse. This lowers the recovery rate to only 25%""