Medicine:Whole blood clotting test
From HandWiki
| Whole blood clotting test | |
|---|---|
| Medical diagnostics | |
| Purpose | to check coagulation mechanism in the blood following a snake bite |
The whole blood clotting test is a blood test used to check the coagulation mechanism in the blood following a snake bite.[1] If the test is positive after a bite in South East Asia it indicates the snake was a viper rather than an elapid.[1] It can also be used to assess the effectiveness of antivenin therapy.[2]
Method
This test indirectly measures the severity of defibrinogenation in envenomed samples.[3] The test is done by collecting 2 ml of venous blood in a dry and clean glass tube. The clot and stability of the formed clot is checked after 20 minutes.[4]
References
- ↑ 1.0 1.1 Guidelines for the management of snake-bites. WHO. 2010. p. 73. ISBN ((978-92-9022-377-4)). http://apps.searo.who.int/PDS_DOCS/B4508.pdf.
- ↑ Chippaux, J. P.; Williams, V.; White, J. (1991). "Snake venom variability: methods of study, results and interpretation". Toxicon 29 (11): 1279–1303. doi:10.1016/0041-0101(91)90116-9. ISSN 0041-0101. PMID 1814005.
- ↑ Sano-Martins, I. S.; Fan, H. W.; Castro, S. C.; Tomy, S. C.; Franca, F. O.; Jorge, M. T.; Kamiguti, A. S.; Warrell, D. A. et al. (September 1994). "Reliability of the simple 20 minute whole blood clotting test (WBCT20) as an indicator of low plasma fibrinogen concentration in patients envenomed by Bothrops snakes. Butantan Institute Antivenom Study Group". Toxicon 32 (9): 1045–1050. doi:10.1016/0041-0101(94)90388-3. ISSN 0041-0101. PMID 7801340.
- ↑ Benjamin, Jordan Max; Chippaux, Jean-Philippe; Sambo, Bio Tamou; Massougbodji, Achille (2018-05-16). "Delayed double reading of whole blood clotting test (WBCT) results at 20 and 30 minutes enhances diagnosis and treatment of viper envenomation". The Journal of Venomous Animals and Toxins Including Tropical Diseases 24: 14. doi:10.1186/s40409-018-0151-1. ISSN 1678-9199. PMID 29796013.
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