Organization:International Molecular Exchange Consortium

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International Molecular Exchange Consortium

The International Molecular Exchange Consortium (IMEx)[1] is a group of the major public providers of molecular interaction data to provide a single, non-redundant set of molecular interactions. Data is captured using a detailed curation model and made available in the PSI-MI standard formats. Participating databases include DIP, IntAct,[2] the Molecular Interaction Database (MINT),[3] MatrixDB,[4] InnateDB, IID, HPIDB, UCL Cardiovascular Gene Annotation, MBInfo, Molecular Connections and UniProt.[1] The group collates the interaction data and prevents duplicate entries in the various databases. The IMEx consortium also supports and contributes to the development of the HUPO-PSI-MI XML format, which is now widely implemented.[1][5]

External references

IMEx website

References

  1. 1.0 1.1 1.2 Orchard, S.; Kerrien, S.; Abbani, S.; Aranda, B.; Bhate, J.; Bidwell, S.; Bridge, A.; Briganti, L. et al. (2012). "Protein interaction data curation: The International Molecular Exchange (IMEx) consortium". Nature Methods 9 (4): 345–350. doi:10.1038/nmeth.1931. PMID 22453911. 
  2. Kerrien, S.; Aranda, B.; Breuza, L.; Bridge, A.; Broackes-Carter, F.; Chen, C.; Duesbury, M.; Dumousseau, M. et al. (24 November 2011). "The IntAct molecular interaction database in 2012". Nucleic Acids Research 40 (D1): D841–D846. doi:10.1093/nar/gkr1088. PMID 22121220. 
  3. Zanzoni, A; Montecchi-Palazzi, L; Quondam, M; Ausiello, G; Helmer-Citterich, M; Cesareni, G (Feb 20, 2002). "MINT: a Molecular INTeraction database.". FEBS Letters 513 (1): 135–40. doi:10.1016/s0014-5793(01)03293-8. PMID 11911893. 
  4. Launay, G. (1 January 2014). "MatrixDB, the extracellular matrix interaction database: updated content, a new navigator and expanded functionalities.". Nucleic Acids Research 43 (Database issue): D321–D327. doi:10.1093/nar/gku1091. PMID 25378329. 
  5. Hermjakob, Henning; Montecchi-Palazzi, Luisa; Bader, Gary; Wojcik, Jérôme; Salwinski, Lukasz; Ceol, Arnaud; Moore, Susan; Orchard, Sandra et al. (2004). "The HUPO PSI's Molecular Interaction format—a community standard for the representation of protein interaction data". Nature Biotechnology 22 (2): 177–183. doi:10.1038/nbt926. PMID 14755292.