View source for Biology:Apo-beta-carotenoid-14',13'-dioxygenase

{{infobox enzyme
| Name       = apo-beta-carotenoid-14',13'-dioxygenase
| EC_number  = 1.13.11.67
| CAS_number =
| GO_code    = 0050588
| image      = 
| width      = 
| caption    = 
| name       =  
}}
'''Apo-beta-carotenoid-14',13'-dioxygenase''' ({{EC number|1.13.11.67}} is an [[Biology:Enzyme|enzyme]] that [[Chemistry:Catalysis|catalyzes]] the [[Chemistry:Chemical reaction|chemical reaction]]

:8'-apo-beta-carotenol + O<sub>2</sub> <math>\rightleftharpoons</math> 14'-apo-beta-carotenal + uncharacterized product

Thus, the two [[Biology:Substrate (biochemistry)|substrates]] of this enzyme are 8'-apo-beta-carotenol and [[Chemistry:Oxygen|oxygen]], whereas its two [[Chemistry:Product|products]] are 14'-apo-beta-carotenal and an uncharacterized product that may be (3E,5E)-7-hydroxy-6-methylhepta-3,5-dien-2-one.

This enzyme belongs to the family of [[Biology:Oxidoreductase|oxidoreductase]]s, specifically those acting on single donors with O<sub>2</sub> as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O with incorporation of one atom of oxygen (internal monooxygenases o internal mixed-function oxidases).  The [[Biology:List of enzymes|systematic name]] of this enzyme class is '''8'-apo-beta-carotenol:O2 oxidoreductase'''.

== References ==
{{reflist|1}}
* {{cite journal|pmid=32747548 |date=2020 |last1=Daruwalla |first1=A. |last2=Zhang |first2=J. |last3=Lee |first3=H. J. |last4=Khadka |first4=N. |last5=Farquhar |first5=E. R. |last6=Shi |first6=W. |last7=von Lintig |first7=J. |last8=Kiser |first8=P. D. |title=Structural basis for carotenoid cleavage by an archaeal carotenoid dioxygenase |journal=Proceedings of the National Academy of Sciences of the United States of America |volume=117 |issue=33 |pages=19914–19925 |doi=10.1073/pnas.2004116117 |pmc=7443882 |bibcode=2020PNAS..11719914D |doi-access=free }}
* {{cite journal | vauthors = Dmitrovskii AA, Gessler NN, Gomboeva SB | title = Enzymatic oxidation of beta-apo-8'-carotenol to beta-apo-14'-carotenal by an enzyme different from beta-carotene-15,15'-dioxygenase | journal = Biochemistry. Biokhimiia | volume = 62 | issue = 7 | pages = 787–92 | date = July 1997 | pmid = 9331970 }}

{{Monooxygenases}}
{{Enzymes}}

[[Category:EC 1.13.12]]
[[Category:Enzymes of unknown structure]]

{{Sourceattribution|Apo-beta-carotenoid-14',13'-dioxygenase}}