Biology:FARME

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Short description: Biological database
Functional Antibiotic Resistance Metagenomic Element
Content
DescriptionCompilation of publicly available predicted proteins and DNA elements that confer Antibiotic Resistance, regulatory elements and mobile genetic elements.
Data types
captured
Antimicrobial resistance genes and DNA Elements
OrganismsBacteria
Contact
Primary citationPMID 28077567
Access
Websitestaff.washington.edu/jwallace/farme/
Download URLDownload
Miscellaneous
Bookmarkable
entities
yes

FARME also known as Functional Antibiotic Resistance Metagenomic Element is a database that compiles publicly available DNA elements and predicted proteins that confer antibiotic resistance, regulatory elements and mobile genetic elements. It is the first database to focus on functional metagenomics. This allows the database to understand 99% of bacteria which cannot be cultured, the relationship between environmental antibiotic resistance sequences and antibiotic genes derived from cultured isolates.[1] This information was derived from 20 metagenomics[2][3][4] projects from GenBank. Also from GenBank are the protein sequence predictions and annotations.

See also

References

  1. Wallace, James C.; Port, Jesse A.; Smith, Marissa N.; Faustman, Elaine M. (2017). "FARME DB: a functional antibiotic resistance element database" (in en). Database 2017: baw165. doi:10.1093/database/baw165. ISSN 1758-0463. PMID 28077567. 
  2. Forsberg, K. J.; Reyes, A.; Wang, B.; Selleck, E. M.; Sommer, M. O. A.; Dantas, G. (2012-08-30). "The Shared Antibiotic Resistome of Soil Bacteria and Human Pathogens". Science 337 (6098): 1107–1111. doi:10.1126/science.1220761. ISSN 0036-8075. PMID 22936781. Bibcode2012Sci...337.1107F. 
  3. Moore, Aimée M.; Patel, Sanket; Forsberg, Kevin J.; Wang, Bin; Bentley, Gayle; Razia, Yasmin; Qin, Xuan; Tarr, Phillip I. et al. (2013-11-13). "Pediatric Fecal Microbiota Harbor Diverse and Novel Antibiotic Resistance Genes". PLOS ONE 8 (11): e78822. doi:10.1371/journal.pone.0078822. ISSN 1932-6203. PMID 24236055. Bibcode2013PLoSO...878822M. 
  4. Parsley, L. C.; Consuegra, E. J.; Kakirde, K. S.; Land, A. M.; Harper, W. F.; Liles, M. R. (2010-04-09). "Identification of Diverse Antimicrobial Resistance Determinants Carried on Bacterial, Plasmid, or Viral Metagenomes from an Activated Sludge Microbial Assemblage". Applied and Environmental Microbiology 76 (11): 3753–3757. doi:10.1128/aem.03080-09. ISSN 0099-2240. PMID 20382816. Bibcode2010ApEnM..76.3753P.