Chemistry:Misonidazole

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Misonidazole
Misonidazole.svg
Names
IUPAC name
(RS)-1-Methoxy-3-(2-nitroimidazol-1-yl)propan-2-ol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
EC Number
  • 236-931-6
KEGG
MeSH D008920
UNII
Properties
C7H11N3O4
Molar mass 201.182 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Tracking categories (test):

Misonidazole is a radiosensitizer that was investigated in clinical trials. It was used in these trials for radiation therapy to cause normally resistant hypoxic tumor cells to become sensitive to the treatment.[1][2]

See also

  • Etanidazole

References

  1. Meißner, Rebecca; Feketeová, Linda; Illenberger, Eugen; Denifl, Stephan (2019). "Reactions in the Radiosensitizer Misonidazole Induced by Low-Energy (0–10 eV) Electrons". International Journal of Molecular Sciences 20 (14): 3496. doi:10.3390/ijms20143496. PMID 31315268. 
  2. Overgaard, Jens (2011). "Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck – A systematic review and meta-analysis". Radiotherapy and Oncology 100 (1): 22–32. doi:10.1016/j.radonc.2011.03.004. PMID 21511351.