Biology:PDE4C
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
cAMP-specific 3',5'-cyclic phosphodiesterase 4C is an enzyme that in humans is encoded by the PDE4C gene.[1]
Tissue localisation
PDE4C is predominantly found in peripheral tissues.[2]
References
- ↑ "Entrez Gene: PDE4C phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5143.
- ↑ Zhang, HT (2009). "Cyclic AMP-Specific Phosphodiesterase-4 as a Target for the Development of Antidepressant Drugs". Current Pharmaceutical Design 15 (14): 1688–1698. doi:10.2174/138161209788168092. PMID 19442182.
Further reading
- "Molecular cloning and functional expression in yeast of a human cAMP-specific phosphodiesterase subtype (PDE IV-C).". FEBS Lett. 358 (3): 305–10. 1995. doi:10.1016/0014-5793(94)01460-I. PMID 7843419.
- "Chromosome localizations of genes for five cAMP-specific phosphodiesterases in man and mouse.". Somat. Cell Mol. Genet. 20 (2): 75–86. 1994. doi:10.1007/BF02290677. PMID 8009369.
- "A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs". Mol. Cell. Biol. 13 (10): 6558–71. 1993. doi:10.1128/mcb.13.10.6558. PMID 8413254.
- "Multiple splice variants of phosphodiesterase PDE4C cloned from human lung and testis". Biochim. Biophys. Acta 1353 (3): 287–97. 1997. doi:10.1016/s0167-4781(97)00080-8. PMID 9349724.
- "Molecular cloning and expression of a human phosphodiesterase 4C". Cell. Signal. 9 (8): 575–85. 1998. doi:10.1016/S0898-6568(97)00072-7. PMID 9429761.
- "Genomic organisation of the human cyclic AMP-specific phosphodiesterase PDE4C gene and its chromosomal localisation to 19p13.1, between RAB3A and JUND". Cell. Signal. 11 (10): 735–42. 2000. doi:10.1016/S0898-6568(99)00037-6. PMID 10574328.
- "HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway". FASEB J. 15 (2): 483–91. 2001. doi:10.1096/fj.00-0354com. PMID 11156964.
- "Phosphodiesterase type 4 isozymes expression in human brain examined by in situ hybridization histochemistry and[3H]rolipram binding autoradiography. Comparison with monkey and rat brain". J. Chem. Neuroanat. 20 (3–4): 349–74. 2001. doi:10.1016/S0891-0618(00)00097-1. PMID 11207431.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays". Science 302 (5653): 2141–4. 2004. doi:10.1126/science.1090100. PMID 14684825.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "The DNA sequence and biology of human chromosome 19". Nature 428 (6982): 529–35. 2004. doi:10.1038/nature02399. PMID 15057824. Bibcode: 2004Natur.428..529G.
- "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. 2004. doi:10.1073/pnas.0404720101. PMID 15302935. Bibcode: 2004PNAS..10112130B.
External links
- Overview of all the structural information available in the PDB for UniProt: Q08493 (cAMP-specific 3',5'-cyclic phosphodiesterase 4C) at the PDBe-KB.
 |  |
