Biology:PGK1

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Phosphoglycerate kinase 1 is an enzyme that in humans is encoded by the PGK1 gene.

Further reading

• "The role of primer recognition proteins in DNA replication: association with nuclear matrix in HeLa cells.". J. Cell Sci.. 101 ( Pt 1): 25–34. 1992. doi:10.1242/jcs.101.1.25. PMID 1533225. 
• "A single amino acid substitution (157 Gly----Val) in a phosphoglycerate kinase variant (PGK Shizuoka) associated with chronic hemolysis and myoglobinuria.". Blood 79 (6): 1582–5. 1992. doi:10.1182/blood.V79.6.1582.1582. PMID 1547346. 
• "Molecular abnormalities of a phosphoglycerate kinase variant generated by spontaneous mutation.". Blood 79 (10): 2759–62. 1992. doi:10.1182/blood.V79.10.2759.bloodjournal79102759. PMID 1586722. 
• "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.". J. Infect. 24 (3): 317–20. 1992. doi:10.1016/S0163-4453(05)80037-4. PMID 1602151. 
• "Immunoelectron microscopic analysis of the intracellular distribution of primer recognition proteins, annexin 2 and phosphoglycerate kinase, in normal and transformed cells.". J. Cell Sci.. 99 ( Pt 4) (4): 751–8. 1992. doi:10.1242/jcs.99.4.751. PMID 1837552. 
• "Molecular defect of a phosphoglycerate kinase variant (PGK-Matsue) associated with hemolytic anemia: Leu----Pro substitution caused by T/A----C/G transition in exon 3.". Blood 77 (6): 1348–52. 1991. doi:10.1182/blood.V77.6.1348.1348. PMID 2001457. 
• "Functional identity of a primer recognition protein as phosphoglycerate kinase.". J. Biol. Chem. 265 (12): 6540–3. 1990. doi:10.1016/S0021-9258(19)39179-3. PMID 2324090. 
• "Limited bidirectional activity of two housekeeping gene promoters: human HPRT and PGK.". Gene 88 (2): 207–13. 1990. doi:10.1016/0378-1119(90)90033-N. PMID 2347494. 
• "Genomic sequencing and methylation analysis by ligation mediated PCR.". Science 246 (4931): 810–3. 1989. doi:10.1126/science.2814502. PMID 2814502. Bibcode: 1989Sci...246..810P. 
• "Structure of the human phosphoglycerate kinase gene and the intron-mediated evolution and dispersal of the nucleotide-binding domain.". Proc. Natl. Acad. Sci. U.S.A. 82 (20): 6965–9. 1985. doi:10.1073/pnas.82.20.6965. PMID 2995995. Bibcode: 1985PNAS...82.6965M. 
• "Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene.". Nature 326 (6112): 501–5. 1987. doi:10.1038/326501a0. PMID 3453121. Bibcode: 1987Natur.326..501M. 
• "Molecular abnormality of phosphoglycerate kinase-Uppsala associated with chronic nonspherocytic hemolytic anemia.". Proc. Natl. Acad. Sci. U.S.A. 77 (9): 5461–5. 1981. doi:10.1073/pnas.77.9.5461. PMID 6933565. 
• "Use of cultured lymphoblastoid cells for the study of abnormal enzymes: molecular abnormality of a phosphoglycerate kinase variant associated with hemolytic anemia.". Proc. Natl. Acad. Sci. U.S.A. 78 (4): 2587–90. 1981. doi:10.1073/pnas.78.4.2587. PMID 6941312. Bibcode: 1981PNAS...78.2587F. 
• "Complete amino acid sequence of human phosphoglycerate kinase. Cyanogen bromide peptides and complete amino acid sequence.". J. Biol. Chem. 255 (13): 6412–20. 1980. doi:10.1016/S0021-9258(18)43754-4. PMID 7391027. 
• "A single amino acid substitution (Asp leads to Asn) in a phosphoglycerate kinase variant (PGK München) associated with enzyme deficiency.". J. Biol. Chem. 255 (13): 6421–3. 1980. doi:10.1016/S0021-9258(18)43755-6. PMID 7391028. 
• "Structure and function of normal and variant human phosphoglycerate kinase.". Hemoglobin 4 (5–6): 601–9. 1981. doi:10.3109/03630268008997730. PMID 7440217. 
• "Construction of a human full-length cDNA bank.". Gene 150 (2): 243–50. 1995. doi:10.1016/0378-1119(94)90433-2. PMID 7821789. 
• "Metaphase chromosome analysis by ligation-mediated PCR: heritable chromatin structure and a comparison of active and inactive X chromosomes.". Proc. Natl. Acad. Sci. U.S.A. 92 (6): 2379–83. 1995. doi:10.1073/pnas.92.6.2379. PMID 7892275. Bibcode: 1995PNAS...92.2379H. 

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Phosphoglycerate kinase 1