Biology:Didemnum proliferum

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Short description: Species of sea squirt

Didemnum proliferum
Scientific classification edit
Domain: Eukaryota
Kingdom: Animalia
Phylum: Chordata
Subphylum: Tunicata
Class: Ascidiacea
Order: Aplousobranchia
Family: Didemnidae
Genus: Didemnum
Species:
D. proliferum
Binomial name
Didemnum proliferum
Kott, 1981

Didemnum proliferum is a rare species of sea squirt in the family Didemnidae.

Research

Didemnum proliferum is of medical interest as it contains shishijimicin molecules, which have been seen to have potent anti-tumor activity in HeLa cells at picomolar concentrations.[1] Shishijimicin A was recently synthesized.[2]

References

  1. Oku, N; Matsunaga, S; Fusetani, N (26 February 2003). "Shishijimicins A-C, novel enediyne antitumor antibiotics from the ascidian Didemnum proliferum(1).". Journal of the American Chemical Society 125 (8): 2044–5. doi:10.1021/ja0296780. PMID 12590521. 
  2. "Rice lab synthesizes cancer-killing compound". http://news.rice.edu/2015/07/13/rice-lab-synthesizes-cancer-killing-compound-2/. Retrieved 2015-07-13. 

Wikidata ☰ Q20686555 entry