Biology:CEP135

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Centrosomal protein of 135 kDa is a protein that in humans is encoded by the CEP135 gene.[1][2][3] It is part of the centrosome throughout the cell cycle, being distributed in the pericentriolar material.[4] CEP135 is required for the centriolar localization of CEP250.[5]

References

  1. "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res 5 (3): 169–76. Dec 1998. doi:10.1093/dnares/5.3.169. PMID 9734811. 
  2. "Proteomic characterization of the human centrosome by protein correlation profiling". Nature 426 (6966): 570–4. Dec 2003. doi:10.1038/nature02166. PMID 14654843. Bibcode2003Natur.426..570A. 
  3. "Entrez Gene: CEP135 centrosomal protein 135kDa". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9662. 
  4. "Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells". J. Cell Biol. 156 (1): 87–99. January 2002. doi:10.1083/jcb.200108088. PMID 11781336. 
  5. "A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization". Exp. Cell Res. 314 (20): 3692–700. December 2008. doi:10.1016/j.yexcr.2008.09.016. PMID 18851962. 

External links

  • Human CEP135 genome location and CEP135 gene details page in the UCSC Genome Browser.
  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Centrosomal protein of 135 kDa

Further reading