Biology:CEP135

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Centrosomal protein of 135 kDa is a protein that in humans is encoded by the CEP135 gene.[1][2][3] It is part of the centrosome throughout the cell cycle, being distributed in the pericentriolar material.[4] CEP135 is required for the centriolar localization of CEP250.[5]

References

  1. ↑ "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res 5 (3): 169–76. Dec 1998. doi:10.1093/dnares/5.3.169. PMID 9734811. 
  2. ↑ "Proteomic characterization of the human centrosome by protein correlation profiling". Nature 426 (6966): 570–4. Dec 2003. doi:10.1038/nature02166. PMID 14654843. Bibcode: 2003Natur.426..570A. 
  3. ↑ "Entrez Gene: CEP135 centrosomal protein 135kDa". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9662. 
  4. ↑ "Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells". J. Cell Biol. 156 (1): 87–99. January 2002. doi:10.1083/jcb.200108088. PMID 11781336. 
  5. ↑ "A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization". Exp. Cell Res. 314 (20): 3692–700. December 2008. doi:10.1016/j.yexcr.2008.09.016. PMID 18851962. 
  • Human CEP135 genome location and CEP135 gene details page in the UCSC Genome Browser.
  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Centrosomal protein of 135 kDa

Further reading