Biology:KRT33A
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Keratin, type I cuticular Ha3-I is a protein that in humans is encoded by the KRT33A gene.[1][2][3]
The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B.[3]
References
- ↑ "A novel human type I hair keratin gene: evidence for two keratin hHa3 isoforms". Mol Biol Rep 20 (3): 155–61. Nov 1995. doi:10.1007/BF00990548. PMID 7565656.
- ↑ "New consensus nomenclature for mammalian keratins". J Cell Biol 174 (2): 169–74. Jul 2006. doi:10.1083/jcb.200603161. PMID 16831889.
- ↑ 3.0 3.1 "Entrez Gene: KRT33A keratin 33A". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3883.
Further reading
- "Human hair keratins". J. Invest. Dermatol. 101 (1 Suppl): 56S–59S. 1993. doi:10.1111/1523-1747.ep12362635. PMID 7686952.
- "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. 2007. doi:10.1038/msb4100134. PMID 17353931.
- "The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain". Differentiation 72 (9–10): 527–40. 2005. doi:10.1111/j.1432-0436.2004.07209006.x. PMID 15617563.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle". J. Biol. Chem. 274 (28): 19874–84. 1999. doi:10.1074/jbc.274.28.19874. PMID 10391933.
- "Characterization of a 190-kilobase pair domain of human type I hair keratin genes". J. Biol. Chem. 273 (41): 26683–91. 1998. doi:10.1074/jbc.273.41.26683. PMID 9756910.
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