Biology:KRT33A

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Keratin, type I cuticular Ha3-I is a protein that in humans is encoded by the KRT33A gene.[1][2][3]

The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B.[3]

References

  1. "A novel human type I hair keratin gene: evidence for two keratin hHa3 isoforms". Mol Biol Rep 20 (3): 155–61. Nov 1995. doi:10.1007/BF00990548. PMID 7565656. 
  2. "New consensus nomenclature for mammalian keratins". J Cell Biol 174 (2): 169–74. Jul 2006. doi:10.1083/jcb.200603161. PMID 16831889. 
  3. 3.0 3.1 "Entrez Gene: KRT33A keratin 33A". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3883. 

Further reading