Biology:Merbecovirus

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Short description: Subgenus of viruses


Merbecovirus
MERS-CoV: structure, attachment, viral entry, and genomic composition
MERS-CoV: structure, attachment, viral entry, and genomic composition
Virus classification e
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Pisuviricota
Class: Pisoniviricetes
Order: Nidovirales
Family: Coronaviridae
Genus: Betacoronavirus
Subgenus: Merbecovirus
Species[1]

Merbecovirus is a subgenus of viruses in the genus Betacoronavirus, including the human pathogen Middle East respiratory syndrome–related coronavirus (MERS-CoV).[1] The viruses in this subgenus were previously known as group 2c coronaviruses.[2][3]

Structure

The viruses of this subgenus, like other coronaviruses, have a lipid bilayer envelope in which the membrane (M), envelope (E) and spike (S) structural proteins are anchored.[4][5]

See also

References

  1. 1.0 1.1 "Virus Taxonomy: 2018 Release" (in en). October 2018. https://ictv.global/taxonomy. Retrieved 24 January 2019. 
  2. Woo, Patrick C. Y.; Wang, Ming; Lau, Susanna K. P.; Xu, Huifang; Poon, Rosana W. S.; Guo, Rongtong; Wong, Beatrice H. L.; Gao, Kai et al. (February 2007). "Comparative Analysis of Twelve Genomes of Three Novel Group 2c and Group 2d Coronaviruses Reveals Unique Group and Subgroup Features". Journal of Virology 81 (4): 1574–1585. doi:10.1128/JVI.02182-06. ISSN 0022-538X. PMID 17121802. "See figure 2.". 
  3. Wong, Antonio C. P.; Li, Xin; Lau, Susanna K. P.; Woo, Patrick C. Y. (2019-02-20). "Global Epidemiology of Bat Coronaviruses". Viruses 11 (2): 174. doi:10.3390/v11020174. ISSN 1999-4915. PMID 30791586. "CoVs are classified into four genera, Alphacoronavirus, Betacoronavirus, Gammacoronavirus and Deltacoronavirus. Within Betacoronavirus, they can be further subclassified into lineages A, B, C and D [1]. In 2018, these four lineages were reclassified as subgenera of Betacoronavirus, and renamed as Embecovirus (previous lineage A), Sarbecovirus (previous lineage B), Merbecovirus (previous lineage C) and Nobecovirus (previous lineage D) [2]. In addition, a fifth subgenus, Hibecovirus, was also included (Figure 1) [2].". 
  4. Lai, Michael M. C.; Cavanagh, David (1997-01-01), Maramorosch, Karl; Murphy, Frederick A.; Shatkin, Aaron J., eds., "The Molecular Biology of Coronaviruses; III. Structure of Virions; A. Virion Morphology" (in en), Advances in Virus Research (Academic Press) 48: 5–6, doi:10.1016/S0065-3527(08)60286-9, PMID 9233431 
  5. Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (2010-08-24). "Coronavirus Genomics and Bioinformatics Analysis". Viruses 2 (8): 1804–1820. doi:10.3390/v2081803. ISSN 1999-4915. PMID 21994708. "The presence of HE genes exclusively in members of Betacoronavirus subgroup A, but not members of Betacoronavirus subgroup B, C and D suggested that the recombination had probably occurred in the ancestor of members of Betacoronavirus subgroup A, after diverging from the ancestor of other subgroups of Betacoronavirus.". 

Wikidata ☰ Q57754679 entry