Biology:SMIM20
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Small integral membrane protein (SMIM) 20 is a protein that in humans is encoded by the SMIM20 gene.[1] SMIM20 acts as a prohormone to the peptide hormone phoenixin which was discovered for the first time in 2013 in rodent sensory ganglia.[2]
In the study of the evolution of nervous systems, SMIM20 together with NUCB2 have been found to have deep homology across all lineages that preceded creatures with central nervous systems, bilaterians, cnidarians, ctenophores, and sponges as well as in choanoflagellates.[3][4]
References
- ↑ "Entrez Gene: Small integral membrane protein 20". https://www.ncbi.nlm.nih.gov/gene/389203.
- ↑ "A novel reproductive peptide, phoenixin". Journal of Neuroendocrinology 25 (2): 206–215. February 2013. doi:10.1111/j.1365-2826.2012.02381.x. PMID 22963497.
- ↑ "Premetazoan Origin of Neuropeptide Signaling". Molecular Biology and Evolution 39 (4): msac051. April 2022. doi:10.1093/molbev/msac051. PMID 35277960.
- ↑ "Brain-Signal Proteins Evolved Before Animals Did" (in en). 3 June 2022. https://www.quantamagazine.org/brain-signal-proteins-evolved-before-animals-did-20220603/.
Further reading
 |  |
