Chemistry:Aconiazide
From HandWiki
Names | |
---|---|
IUPAC name
2-[2-[(E)-(Pyridine-4-carbonylhydrazinylidene)methyl]phenoxy]acetic acid
| |
Other names
Isonicophen; Phenoxalid
| |
Identifiers | |
3D model (JSmol)
|
|
ChEMBL | |
ChemSpider | |
PubChem CID
|
|
UNII | |
| |
| |
Properties | |
C15H13N3O4 | |
Molar mass | 299.286 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Aconiazide is an anti-tuberculosis medication. It is a prodrug of isoniazide that was developed and studied for its lower toxicity,[1][2] but it does not appear to be marketed anywhere in the world in 2021.
References
- ↑ Hansen Jr, EB; Dooley, KL; Thompson Jr, HC (1995). "High-performance liquid chromatographic analysis of the antituberculosis drugs aconiazide and isoniazid". Journal of Chromatography B 670 (2): 259–66. doi:10.1016/0378-4347(95)00176-x. PMID 8548016. https://zenodo.org/record/1258541.
- ↑ Peloquin, C. A.; James, G. T.; Craig, L. D.; Kim, M; McCarthy, E. A.; Iklé, D; Iseman, M. D. (1994). "Pharmacokinetic evaluation of aconiazide, a potentially less toxic isoniazid prodrug". Pharmacotherapy 14 (4): 415–23. doi:10.1002/j.1875-9114.1994.tb02831.x. PMID 7937278. https://accpjournals.onlinelibrary.wiley.com/doi/abs/10.1002/j.1875-9114.1994.tb02831.x.
Original source: https://en.wikipedia.org/wiki/Aconiazide.
Read more |